Dispersion of refractoriness and induction of reentry due to chaos synchronization in a model of cardiac tissue

Yuanfang Xie, Gang Hu, Daisuke Sato, James N. Weiss, Alan Garfinkel, Zhilin Qu

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Ventricular fibrillation is a lethal condition caused by multiple chaotically wandering electrical wavelets in the heart, reentering their own and each otherâ™s territories. The development of effective therapies requires a detailed understanding of how these reentrant waves are initiated. In this Letter, we demonstrate a novel mechanism for inducing reentry, in which chaos synchronization causes large-scale heterogeneities of refractoriness transverse to the direction of propagation. These regions of increased refractoriness create localized conduction block, which induces spiral wave reentry.

Original languageEnglish (US)
Article number118101
JournalPhysical Review Letters
Volume99
Issue number11
DOIs
StatePublished - Sep 12 2007

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reentry
chaos
synchronism
induction
fibrillation
therapy
conduction
propagation
causes

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Dispersion of refractoriness and induction of reentry due to chaos synchronization in a model of cardiac tissue. / Xie, Yuanfang; Hu, Gang; Sato, Daisuke; Weiss, James N.; Garfinkel, Alan; Qu, Zhilin.

In: Physical Review Letters, Vol. 99, No. 11, 118101, 12.09.2007.

Research output: Contribution to journalArticle

Xie, Yuanfang ; Hu, Gang ; Sato, Daisuke ; Weiss, James N. ; Garfinkel, Alan ; Qu, Zhilin. / Dispersion of refractoriness and induction of reentry due to chaos synchronization in a model of cardiac tissue. In: Physical Review Letters. 2007 ; Vol. 99, No. 11.
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