Abstract
Because thyroid hormones exert regulatory effects on multiple organ systems, thyroid function should be aggressively evaluated and abnormal function treated in patients who require surgery. Thyroid hormones also significantly affect the metabolism of many drugs, and dose adjustments may be required when function is abnormal. Medical consultants performing preoperative evaluations should include clinical assessments of thyroid function and perform confirmatory tests when indicated. The adult thyroid gland weighs 15–20 g, typically consists of two lobes connected by an isthmus, and is located just below the cricoid cartilage. A remnant of the thyroglossal duct, the pyramidal lobe may be noted arising superiorly from the isthmus or medial side of a lobe. Enlargement of the pyramidal lobe indicates a diffuse thyroidal abnormality. The thyroid gland consists of follicles, which are spheres lined by a single layer of cuboidal cells and are filled with a colloid that is composed primarily of thyroglobulin. A rich capillary network surrounds the follicles, explaining why a bruit is sometimes heard over hyperactive, enlarged thyroid glands. Scattered throughout the thyroid are calcitonin-secreting perifollicular cells. Hyperplasic or malignant transformation of these cells does not result in abnormalities of thyroid function [1–3].
| Original language | English (US) |
|---|---|
| Title of host publication | Medical Management of the Surgical Patient: A Textbook of Perioperative Medicine, Fifth Edition |
| Publisher | Cambridge University Press |
| Pages | 350-357 |
| Number of pages | 8 |
| ISBN (Print) | 9780511920660, 9781107009165 |
| DOIs | |
| State | Published - Jan 1 2010 |
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ASJC Scopus subject areas
- Medicine(all)
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Disorders of the thyroid. / Prescott, Pamela T.
Medical Management of the Surgical Patient: A Textbook of Perioperative Medicine, Fifth Edition. Cambridge University Press, 2010. p. 350-357.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Disorders of the thyroid
AU - Prescott, Pamela T
PY - 2010/1/1
Y1 - 2010/1/1
N2 - Because thyroid hormones exert regulatory effects on multiple organ systems, thyroid function should be aggressively evaluated and abnormal function treated in patients who require surgery. Thyroid hormones also significantly affect the metabolism of many drugs, and dose adjustments may be required when function is abnormal. Medical consultants performing preoperative evaluations should include clinical assessments of thyroid function and perform confirmatory tests when indicated. The adult thyroid gland weighs 15–20 g, typically consists of two lobes connected by an isthmus, and is located just below the cricoid cartilage. A remnant of the thyroglossal duct, the pyramidal lobe may be noted arising superiorly from the isthmus or medial side of a lobe. Enlargement of the pyramidal lobe indicates a diffuse thyroidal abnormality. The thyroid gland consists of follicles, which are spheres lined by a single layer of cuboidal cells and are filled with a colloid that is composed primarily of thyroglobulin. A rich capillary network surrounds the follicles, explaining why a bruit is sometimes heard over hyperactive, enlarged thyroid glands. Scattered throughout the thyroid are calcitonin-secreting perifollicular cells. Hyperplasic or malignant transformation of these cells does not result in abnormalities of thyroid function [1–3].
AB - Because thyroid hormones exert regulatory effects on multiple organ systems, thyroid function should be aggressively evaluated and abnormal function treated in patients who require surgery. Thyroid hormones also significantly affect the metabolism of many drugs, and dose adjustments may be required when function is abnormal. Medical consultants performing preoperative evaluations should include clinical assessments of thyroid function and perform confirmatory tests when indicated. The adult thyroid gland weighs 15–20 g, typically consists of two lobes connected by an isthmus, and is located just below the cricoid cartilage. A remnant of the thyroglossal duct, the pyramidal lobe may be noted arising superiorly from the isthmus or medial side of a lobe. Enlargement of the pyramidal lobe indicates a diffuse thyroidal abnormality. The thyroid gland consists of follicles, which are spheres lined by a single layer of cuboidal cells and are filled with a colloid that is composed primarily of thyroglobulin. A rich capillary network surrounds the follicles, explaining why a bruit is sometimes heard over hyperactive, enlarged thyroid glands. Scattered throughout the thyroid are calcitonin-secreting perifollicular cells. Hyperplasic or malignant transformation of these cells does not result in abnormalities of thyroid function [1–3].
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UR - http://www.scopus.com/inward/citedby.url?scp=84923390143&partnerID=8YFLogxK
U2 - 10.1017/CBO9780511920660.033
DO - 10.1017/CBO9780511920660.033
M3 - Chapter
AN - SCOPUS:84923390143
SN - 9780511920660
SN - 9781107009165
SP - 350
EP - 357
BT - Medical Management of the Surgical Patient: A Textbook of Perioperative Medicine, Fifth Edition
PB - Cambridge University Press
ER -