Abstract
Acne fulminans is an uncommon and debilitating disease that presents as an acute eruption of nodular and ulcerative acne lesions in association with systemic symptoms. It occurs commonly during treatment of severe acne (eg, acne conglobata) with isotretinoin in young adolescent male patients. Isotretinoin and doxycycline also can potentially induce development of neutrophilic dermatoses in patients with severe acne lesions, which are characterized by the acute appearance of painful ulcerative papulonodules accompanied by systemic symptoms including fever and leukocytosis. We report a challenging case of a 13-year-old adolescent boy who acutely developed hundreds of ulcerative plaques as well as systemic symptoms after being treated with doxycycline and isotretinoin for acne conglobata. He was treated with prednisone, dapsone, and colchicine and had to switch to cyclosporine to achieve relief from his condition. Copyright Cutis 2017.
| Original language | English (US) |
|---|---|
| Pages (from-to) | E23-E26 |
| Journal | Cutis |
| Volume | 100 |
| Issue number | 6 |
| State | Published - Dec 1 2017 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Dermatology
Cite this
Disfiguring ulcerative neutrophilic dermatosis secondary to doxycycline and isotretinoin in an adolescent boy with acne conglobata. / Sotoodian, Bahman; Kuzel, Paul; Brassard, Alain; Fiorillo, Loretta.
In: Cutis, Vol. 100, No. 6, 01.12.2017, p. E23-E26.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Disfiguring ulcerative neutrophilic dermatosis secondary to doxycycline and isotretinoin in an adolescent boy with acne conglobata
AU - Sotoodian, Bahman
AU - Kuzel, Paul
AU - Brassard, Alain
AU - Fiorillo, Loretta
PY - 2017/12/1
Y1 - 2017/12/1
N2 - Acne fulminans is an uncommon and debilitating disease that presents as an acute eruption of nodular and ulcerative acne lesions in association with systemic symptoms. It occurs commonly during treatment of severe acne (eg, acne conglobata) with isotretinoin in young adolescent male patients. Isotretinoin and doxycycline also can potentially induce development of neutrophilic dermatoses in patients with severe acne lesions, which are characterized by the acute appearance of painful ulcerative papulonodules accompanied by systemic symptoms including fever and leukocytosis. We report a challenging case of a 13-year-old adolescent boy who acutely developed hundreds of ulcerative plaques as well as systemic symptoms after being treated with doxycycline and isotretinoin for acne conglobata. He was treated with prednisone, dapsone, and colchicine and had to switch to cyclosporine to achieve relief from his condition. Copyright Cutis 2017.
AB - Acne fulminans is an uncommon and debilitating disease that presents as an acute eruption of nodular and ulcerative acne lesions in association with systemic symptoms. It occurs commonly during treatment of severe acne (eg, acne conglobata) with isotretinoin in young adolescent male patients. Isotretinoin and doxycycline also can potentially induce development of neutrophilic dermatoses in patients with severe acne lesions, which are characterized by the acute appearance of painful ulcerative papulonodules accompanied by systemic symptoms including fever and leukocytosis. We report a challenging case of a 13-year-old adolescent boy who acutely developed hundreds of ulcerative plaques as well as systemic symptoms after being treated with doxycycline and isotretinoin for acne conglobata. He was treated with prednisone, dapsone, and colchicine and had to switch to cyclosporine to achieve relief from his condition. Copyright Cutis 2017.
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UR - http://www.scopus.com/inward/citedby.url?scp=85041386624&partnerID=8YFLogxK
M3 - Article
C2 - 29360905
AN - SCOPUS:85041386624
VL - 100
SP - E23-E26
JO - Cutis
JF - Cutis
SN - 0011-4162
IS - 6
ER -