Diseases Produced by Clostridium perfringens Type C

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Intestinal infection by Clostridium perfringens Type C causes necrotizing enteritis or enterocolitis in domestic animals and humans. In humans, type C disease is also known as enteritis necroticans, pigbel, or darmbrand. The disease has been reproduced experimentally in pigs, sheep, calves, and goats, while rabbits, and mice, and guinea pigs have been used in experimental models to study diverse aspects of the pathogenesis of type C disease. This chapter discusses the etiology, epidemiology, pathogenesis, clinical signs, prophylaxis, and treatment of diseases produced by C. perfringens Type C. The characteristic microscopic lesion of natural disease in all species is severe necrotizing and hemorrhagic enteritis or colitis with mucosal or submucosal thrombosis. C. perfringens vaccines for veterinary use are mostly prepared from semi-purified supernatants of cultures of C. perfringens types A, B, C, and D, or a combination of these types.

Original languageEnglish (US)
Title of host publicationClostridial Diseases in Animals
Publisherwiley
Pages143-155
Number of pages13
ISBN (Electronic)9781118728291
ISBN (Print)9781118728406
DOIs
StatePublished - Apr 8 2016

Fingerprint

Clostridium perfringens C
Clostridium perfringens
enteritis
pathogenesis
Enteritis
hemorrhagic enteritis
Clostridium perfringens A
enterocolitis
thrombosis
colitis
domestic animals
lesions (animal)
guinea pigs
etiology
epidemiology
disease control
goats
rabbits
calves
vaccines

Keywords

  • C. perfringens Type C
  • Hemorrhagic enteritis
  • Necrotizing enteritis
  • Submucosal thrombosis

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Diseases Produced by Clostridium perfringens Type C. / Diab, Santiago S.

Clostridial Diseases in Animals. wiley, 2016. p. 143-155.

Research output: Chapter in Book/Report/Conference proceedingChapter

Diab, Santiago S. / Diseases Produced by Clostridium perfringens Type C. Clostridial Diseases in Animals. wiley, 2016. pp. 143-155
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