Abstract
Clostridium perfringens type A is frequently associated with enteric disease of poultry, ruminants, horses, pigs and dogs. This chapter discusses some of the diseases caused by the C. perfringens bacterium such as Yellow lamb disease, hemorrhagic canine gastroenteritis, and C. perfringens enterotoxin (CPE)-associated diarrhea. It is generally accepted that a presumptive diagnosis of yellow lamb disease can be established based on clinical, gross, and microscopic findings. Many vaccines against the different types of C. perfringens used around the world serendipitously contain C. perfringens alpha toxin (CPA) toxoid, and it is possible that they afford at least some level of protection to animals against yellow lamb disease. C. perfringens beta 2 toxin (CPB2)-producing C. perfringens type A strains have been associated with enteric disease in several animal species, including horses, pigs, sheep, and goats. In most cases, the evidence is based solely on isolation of CPB2-positive C. perfringens from sick animals.
| Original language | English (US) |
|---|---|
| Title of host publication | Clostridial Diseases in Animals |
| Publisher | wiley |
| Pages | 107-116 |
| Number of pages | 10 |
| ISBN (Electronic) | 9781118728291 |
| ISBN (Print) | 9781118728406 |
| DOIs | |
| State | Published - Apr 8 2016 |
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Keywords
- Beta 2 toxin
- Clostridium perfringens type A
- CPE-associated diarrhea
- Hemorrhagic canine gastroenteritis
- Yellow lamb disease
ASJC Scopus subject areas
- veterinary(all)
Cite this
Diseases Produced by Clostridium perfringens Type A in Mammalian Species. / Uzal, Francisco A.
Clostridial Diseases in Animals. wiley, 2016. p. 107-116.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Diseases Produced by Clostridium perfringens Type A in Mammalian Species
AU - Uzal, Francisco A
PY - 2016/4/8
Y1 - 2016/4/8
N2 - Clostridium perfringens type A is frequently associated with enteric disease of poultry, ruminants, horses, pigs and dogs. This chapter discusses some of the diseases caused by the C. perfringens bacterium such as Yellow lamb disease, hemorrhagic canine gastroenteritis, and C. perfringens enterotoxin (CPE)-associated diarrhea. It is generally accepted that a presumptive diagnosis of yellow lamb disease can be established based on clinical, gross, and microscopic findings. Many vaccines against the different types of C. perfringens used around the world serendipitously contain C. perfringens alpha toxin (CPA) toxoid, and it is possible that they afford at least some level of protection to animals against yellow lamb disease. C. perfringens beta 2 toxin (CPB2)-producing C. perfringens type A strains have been associated with enteric disease in several animal species, including horses, pigs, sheep, and goats. In most cases, the evidence is based solely on isolation of CPB2-positive C. perfringens from sick animals.
AB - Clostridium perfringens type A is frequently associated with enteric disease of poultry, ruminants, horses, pigs and dogs. This chapter discusses some of the diseases caused by the C. perfringens bacterium such as Yellow lamb disease, hemorrhagic canine gastroenteritis, and C. perfringens enterotoxin (CPE)-associated diarrhea. It is generally accepted that a presumptive diagnosis of yellow lamb disease can be established based on clinical, gross, and microscopic findings. Many vaccines against the different types of C. perfringens used around the world serendipitously contain C. perfringens alpha toxin (CPA) toxoid, and it is possible that they afford at least some level of protection to animals against yellow lamb disease. C. perfringens beta 2 toxin (CPB2)-producing C. perfringens type A strains have been associated with enteric disease in several animal species, including horses, pigs, sheep, and goats. In most cases, the evidence is based solely on isolation of CPB2-positive C. perfringens from sick animals.
KW - Beta 2 toxin
KW - Clostridium perfringens type A
KW - CPE-associated diarrhea
KW - Hemorrhagic canine gastroenteritis
KW - Yellow lamb disease
UR - http://www.scopus.com/inward/record.url?scp=85024855532&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85024855532&partnerID=8YFLogxK
U2 - 10.1002/9781118728291.ch8
DO - 10.1002/9781118728291.ch8
M3 - Chapter
AN - SCOPUS:85024855532
SN - 9781118728406
SP - 107
EP - 116
BT - Clostridial Diseases in Animals
PB - wiley
ER -