Abstract
A population-based, case-control study of sporadic salmonellosis was conducted in 1988 and 1989 in four northern California counties. The study included 120 patients and 265 control subjects. Conditional logistic regression analysis (adjusted for age) revealed that patients were more likely to consume undercooked chicken prior to the onset of disease (odds ratio [OR], 23.57; 95% confidence interval [CI], 2.89 to 192.30). Elevated associations were also found with recent travel to foreign countries (OR, 9.69; 95% CI, 3.18 to 29.56), diabetes (OR, 6.29; 95% CI, 1.56 to 25.34), hormonal replacement therapy (principally conjugated estrogen) in older women (OR, 4.20; 95% CI, 1.82 to 9.71), and antibiotic therapy prior to illness (OR, 1.96; 95% CI, 0.86 to 4.37). The problems of studying self-selected cases that may lead to alternative explanations for these findings are also discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 683-696 |
| Number of pages | 14 |
| Journal | Annals of Epidemiology |
| Volume | 2 |
| Issue number | 5 |
| DOIs | |
| State | Published - 1992 |
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Keywords
- Antibiotics
- diabetes mellitus
- estrogens
- gastrointestinal diseases
- poultry products
- salmonella infections
ASJC Scopus subject areas
- Medicine(all)
- Epidemiology
- Public Health, Environmental and Occupational Health
Cite this
Disease determinants of sporadic salmonellosis in four Northern California counties A case-control study of older children and adults. / Kass, Philip H; Farver, Thomas B; Beaumont, James J.; Genigeorgis, Constantin; Stevens, Fredric.
In: Annals of Epidemiology, Vol. 2, No. 5, 1992, p. 683-696.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Disease determinants of sporadic salmonellosis in four Northern California counties A case-control study of older children and adults
AU - Kass, Philip H
AU - Farver, Thomas B
AU - Beaumont, James J.
AU - Genigeorgis, Constantin
AU - Stevens, Fredric
PY - 1992
Y1 - 1992
N2 - A population-based, case-control study of sporadic salmonellosis was conducted in 1988 and 1989 in four northern California counties. The study included 120 patients and 265 control subjects. Conditional logistic regression analysis (adjusted for age) revealed that patients were more likely to consume undercooked chicken prior to the onset of disease (odds ratio [OR], 23.57; 95% confidence interval [CI], 2.89 to 192.30). Elevated associations were also found with recent travel to foreign countries (OR, 9.69; 95% CI, 3.18 to 29.56), diabetes (OR, 6.29; 95% CI, 1.56 to 25.34), hormonal replacement therapy (principally conjugated estrogen) in older women (OR, 4.20; 95% CI, 1.82 to 9.71), and antibiotic therapy prior to illness (OR, 1.96; 95% CI, 0.86 to 4.37). The problems of studying self-selected cases that may lead to alternative explanations for these findings are also discussed.
AB - A population-based, case-control study of sporadic salmonellosis was conducted in 1988 and 1989 in four northern California counties. The study included 120 patients and 265 control subjects. Conditional logistic regression analysis (adjusted for age) revealed that patients were more likely to consume undercooked chicken prior to the onset of disease (odds ratio [OR], 23.57; 95% confidence interval [CI], 2.89 to 192.30). Elevated associations were also found with recent travel to foreign countries (OR, 9.69; 95% CI, 3.18 to 29.56), diabetes (OR, 6.29; 95% CI, 1.56 to 25.34), hormonal replacement therapy (principally conjugated estrogen) in older women (OR, 4.20; 95% CI, 1.82 to 9.71), and antibiotic therapy prior to illness (OR, 1.96; 95% CI, 0.86 to 4.37). The problems of studying self-selected cases that may lead to alternative explanations for these findings are also discussed.
KW - Antibiotics
KW - diabetes mellitus
KW - estrogens
KW - gastrointestinal diseases
KW - poultry products
KW - salmonella infections
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UR - http://www.scopus.com/inward/citedby.url?scp=0026674786&partnerID=8YFLogxK
U2 - 10.1016/1047-2797(92)90013-G
DO - 10.1016/1047-2797(92)90013-G
M3 - Article
C2 - 1342320
AN - SCOPUS:0026674786
VL - 2
SP - 683
EP - 696
JO - Annals of Epidemiology
JF - Annals of Epidemiology
SN - 1047-2797
IS - 5
ER -