Disease determinants of sporadic salmonellosis in four Northern California counties A case-control study of older children and adults

Philip H Kass, Thomas B Farver, James J. Beaumont, Constantin Genigeorgis, Fredric Stevens

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A population-based, case-control study of sporadic salmonellosis was conducted in 1988 and 1989 in four northern California counties. The study included 120 patients and 265 control subjects. Conditional logistic regression analysis (adjusted for age) revealed that patients were more likely to consume undercooked chicken prior to the onset of disease (odds ratio [OR], 23.57; 95% confidence interval [CI], 2.89 to 192.30). Elevated associations were also found with recent travel to foreign countries (OR, 9.69; 95% CI, 3.18 to 29.56), diabetes (OR, 6.29; 95% CI, 1.56 to 25.34), hormonal replacement therapy (principally conjugated estrogen) in older women (OR, 4.20; 95% CI, 1.82 to 9.71), and antibiotic therapy prior to illness (OR, 1.96; 95% CI, 0.86 to 4.37). The problems of studying self-selected cases that may lead to alternative explanations for these findings are also discussed.

Original languageEnglish (US)
Pages (from-to)683-696
Number of pages14
JournalAnnals of Epidemiology
Volume2
Issue number5
DOIs
StatePublished - 1992

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Salmonella Infections
Case-Control Studies
Odds Ratio
Confidence Intervals
Conjugated (USP) Estrogens
Chickens
Logistic Models
Regression Analysis
Anti-Bacterial Agents
Therapeutics
Population

Keywords

  • Antibiotics
  • diabetes mellitus
  • estrogens
  • gastrointestinal diseases
  • poultry products
  • salmonella infections

ASJC Scopus subject areas

  • Medicine(all)
  • Epidemiology
  • Public Health, Environmental and Occupational Health

Cite this

Disease determinants of sporadic salmonellosis in four Northern California counties A case-control study of older children and adults. / Kass, Philip H; Farver, Thomas B; Beaumont, James J.; Genigeorgis, Constantin; Stevens, Fredric.

In: Annals of Epidemiology, Vol. 2, No. 5, 1992, p. 683-696.

Research output: Contribution to journalArticle

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