Disease and pathological conditions of an endangered rodent, microtus californicus scirpensis, in a captive-rearing facility and in the wild

Janet Foley, Nora Allan, Risa Pesapane, Amanda Johnson, Leslie Woods, Laurie Brignolo, Abigail Luce, Deana L. Clifford, Denise M. Imai

Research output: Contribution to journalArticle

Abstract

Causes of morbidity and mortality and a survey of infectious disease agents were collated from wild and colony-raised endangered Amargosa voles (Microtus californicus scirpensis). Six voles from the wild and 295 voles in the captive-breeding colony were included in the study upon identification of an infectious agent during screening, identification of clinical signs of disease, or finding a pathological condition or infectious agent on necropsy. Findings included 28 significant or incidental pathological conditions of seven organ systems and 19 parasitic, viral, bacterial, or fungal agents. Several voles captured in the wild had fungal osteomyelitis of the tail that disseminated systemically in a vole brought from the wild to the colony and may have been caused by a Penicillium sp. Three voles reintroduced from the colony to the wild experienced inanition and subsequent severe hepatic and moderate renal tubular lipidosis. The most common significant pathological conditions in colonyreared voles were chronic interstitial nephritis with proteinosis; cardiomyopathy; trichobezoars that, in intestines or cecocolic junctions, sometimes induced local rupture or infarction with peritonitis; multifocal gastrointestinal ulceration and colibacillosis; acute renal tubular necrosis or nephritis; sepsis; hepatic and renal lipidosis; molar apical elongation sometimes progressing to invasion of the calvarium; and mammary tumors. Uncommon diagnoses included intervertebral disc disease; microvascular dysplasia; and multifocal bacterial abscessation. Common or clinically important infectious agents included Demodex sp. mites in hair follicles, Demodex sp. in esophageal mucosa, and an outbreak of tropical rat mites thought to have been introduced via the straw bedding; gastrointestinal Helicobacter sp.; attaching and effacing Escherichia coli; and Citrobacter braakii, a possible zoonotic bacterium. This survey of species-specific diseases and pathogens was possible because the established health surveillance program that is part of the species recovery plan allowed for monitoring of voles throughout the duration of their natural life spans in captivity.

Original languageEnglish (US)
Pages (from-to)758-768
Number of pages11
JournalJournal of Zoo and Wildlife Medicine
Volume50
Issue number4
DOIs
StatePublished - Jan 9 2020

Fingerprint

Arvicolinae
Rodentia
rodents
rearing
Demodex
Lipidoses
nephritis
pathogens
kidneys
Mites
Kidney
Citrobacter braakii
Ornithonyssus bacoti
trichobezoars
digestive tract mucosa
Helicobacter
Bezoars
intervertebral disks
osteomyelitis
sepsis (infection)

Keywords

  • Amargosa vole
  • endangered species
  • Microtus californicus scirpensis
  • mites
  • rodent
  • trichobezoar

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Disease and pathological conditions of an endangered rodent, microtus californicus scirpensis, in a captive-rearing facility and in the wild. / Foley, Janet; Allan, Nora; Pesapane, Risa; Johnson, Amanda; Woods, Leslie; Brignolo, Laurie; Luce, Abigail; Clifford, Deana L.; Imai, Denise M.

In: Journal of Zoo and Wildlife Medicine, Vol. 50, No. 4, 09.01.2020, p. 758-768.

Research output: Contribution to journalArticle

Foley, Janet ; Allan, Nora ; Pesapane, Risa ; Johnson, Amanda ; Woods, Leslie ; Brignolo, Laurie ; Luce, Abigail ; Clifford, Deana L. ; Imai, Denise M. / Disease and pathological conditions of an endangered rodent, microtus californicus scirpensis, in a captive-rearing facility and in the wild. In: Journal of Zoo and Wildlife Medicine. 2020 ; Vol. 50, No. 4. pp. 758-768.
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