Direct visualization of phase transition dynamics in binary supported phospholipid bilayers using imaging ellipsometry

Alan W. Szmodis, Craig D. Blanchette, Andrey A. Levchenko, Alexandra Navrotsky, Marjorie L. Longo, Christine A. Orme, Atul N. Parikh

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Via imaging ellipsometry, we study the phase transition dynamics induced by selective gelation of one component in a binary supported phopholipid bilayer. We find the modulation of two attendant morphological features: emergence of extended defect chains due to a net change in the molecular areas and fractal-like domains suggesting weak line tension. A time-lapse analysis of the ellipsometric images reveals the cluster size of 4-20 molecules undergoing gelation indicating weak cooperativity. These results demonstrate the use of ellipsometry for in situ, label-free, non-contact, and large-area imaging of dynamics in interfacial films.

Original languageEnglish (US)
Pages (from-to)1161-1164
Number of pages4
JournalSoft Matter
Volume4
Issue number6
DOIs
StatePublished - 2008

Fingerprint

Ellipsometry
gelation
Gelation
ellipsometry
Phospholipids
Visualization
Phase transitions
Imaging techniques
Fractals
Labels
fractals
Modulation
modulation
Defects
Molecules
defects
molecules

ASJC Scopus subject areas

  • Chemistry (miscellaneous)

Cite this

Szmodis, A. W., Blanchette, C. D., Levchenko, A. A., Navrotsky, A., Longo, M. L., Orme, C. A., & Parikh, A. N. (2008). Direct visualization of phase transition dynamics in binary supported phospholipid bilayers using imaging ellipsometry. Soft Matter, 4(6), 1161-1164. https://doi.org/10.1039/b801390j

Direct visualization of phase transition dynamics in binary supported phospholipid bilayers using imaging ellipsometry. / Szmodis, Alan W.; Blanchette, Craig D.; Levchenko, Andrey A.; Navrotsky, Alexandra; Longo, Marjorie L.; Orme, Christine A.; Parikh, Atul N.

In: Soft Matter, Vol. 4, No. 6, 2008, p. 1161-1164.

Research output: Contribution to journalArticle

Szmodis, AW, Blanchette, CD, Levchenko, AA, Navrotsky, A, Longo, ML, Orme, CA & Parikh, AN 2008, 'Direct visualization of phase transition dynamics in binary supported phospholipid bilayers using imaging ellipsometry', Soft Matter, vol. 4, no. 6, pp. 1161-1164. https://doi.org/10.1039/b801390j
Szmodis, Alan W. ; Blanchette, Craig D. ; Levchenko, Andrey A. ; Navrotsky, Alexandra ; Longo, Marjorie L. ; Orme, Christine A. ; Parikh, Atul N. / Direct visualization of phase transition dynamics in binary supported phospholipid bilayers using imaging ellipsometry. In: Soft Matter. 2008 ; Vol. 4, No. 6. pp. 1161-1164.
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