Dipolar cycloadditions in solid-phase organic synthesis (SPOS)

Eric J. Kantorowski, Mark J. Kurth

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

We present a concise review of polymer-supported 1,3-dipolar cycloaddition reactions. Nitrile oxide and azomethine ylides constitute the two types of 1,3-dipoles which have been used in conjunction with solid-phase organic synthesis. These cycloaddition reactions on solid phase are generally of equal or greater efficiency than the analogous solution-phase reactions.

Original languageEnglish (US)
Pages (from-to)207-216
Number of pages10
JournalMolecular Diversity
Volume2
Issue number4
StatePublished - 1997

Fingerprint

Synthetic Chemistry Techniques
Solid-Phase Synthesis Techniques
Cycloaddition
Cycloaddition Reaction
cycloaddition
solid phases
Nitriles
synthesis
Oxides
Polymers
nitriles
dipoles
oxides
polymers
azomethine

Keywords

  • 1,3-Dipolar cycloadditions
  • [3+2] Cycloadditions
  • Azomethine ylide
  • Nitrile oxide ylide
  • Solid-phase organic synthesis (SPOS)

ASJC Scopus subject areas

  • Chemistry (miscellaneous)
  • Drug Discovery
  • Organic Chemistry

Cite this

Kantorowski, E. J., & Kurth, M. J. (1997). Dipolar cycloadditions in solid-phase organic synthesis (SPOS). Molecular Diversity, 2(4), 207-216.

Dipolar cycloadditions in solid-phase organic synthesis (SPOS). / Kantorowski, Eric J.; Kurth, Mark J.

In: Molecular Diversity, Vol. 2, No. 4, 1997, p. 207-216.

Research output: Contribution to journalArticle

Kantorowski, EJ & Kurth, MJ 1997, 'Dipolar cycloadditions in solid-phase organic synthesis (SPOS)', Molecular Diversity, vol. 2, no. 4, pp. 207-216.
Kantorowski, Eric J. ; Kurth, Mark J. / Dipolar cycloadditions in solid-phase organic synthesis (SPOS). In: Molecular Diversity. 1997 ; Vol. 2, No. 4. pp. 207-216.
@article{d935269b50564c0296a28053dc840186,
title = "Dipolar cycloadditions in solid-phase organic synthesis (SPOS)",
abstract = "We present a concise review of polymer-supported 1,3-dipolar cycloaddition reactions. Nitrile oxide and azomethine ylides constitute the two types of 1,3-dipoles which have been used in conjunction with solid-phase organic synthesis. These cycloaddition reactions on solid phase are generally of equal or greater efficiency than the analogous solution-phase reactions.",
keywords = "1,3-Dipolar cycloadditions, [3+2] Cycloadditions, Azomethine ylide, Nitrile oxide ylide, Solid-phase organic synthesis (SPOS)",
author = "Kantorowski, {Eric J.} and Kurth, {Mark J.}",
year = "1997",
language = "English (US)",
volume = "2",
pages = "207--216",
journal = "Molecular Diversity",
issn = "1381-1991",
publisher = "Springer Netherlands",
number = "4",

}

TY - JOUR

T1 - Dipolar cycloadditions in solid-phase organic synthesis (SPOS)

AU - Kantorowski, Eric J.

AU - Kurth, Mark J.

PY - 1997

Y1 - 1997

N2 - We present a concise review of polymer-supported 1,3-dipolar cycloaddition reactions. Nitrile oxide and azomethine ylides constitute the two types of 1,3-dipoles which have been used in conjunction with solid-phase organic synthesis. These cycloaddition reactions on solid phase are generally of equal or greater efficiency than the analogous solution-phase reactions.

AB - We present a concise review of polymer-supported 1,3-dipolar cycloaddition reactions. Nitrile oxide and azomethine ylides constitute the two types of 1,3-dipoles which have been used in conjunction with solid-phase organic synthesis. These cycloaddition reactions on solid phase are generally of equal or greater efficiency than the analogous solution-phase reactions.

KW - 1,3-Dipolar cycloadditions

KW - [3+2] Cycloadditions

KW - Azomethine ylide

KW - Nitrile oxide ylide

KW - Solid-phase organic synthesis (SPOS)

UR - http://www.scopus.com/inward/record.url?scp=0031114071&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031114071&partnerID=8YFLogxK

M3 - Article

C2 - 9249756

AN - SCOPUS:0031114071

VL - 2

SP - 207

EP - 216

JO - Molecular Diversity

JF - Molecular Diversity

SN - 1381-1991

IS - 4

ER -