Dimsyl anion in the monoalkylation of solid-phase alkyl sulfones

Wei Chieh Cheng, Chu Chung Lin, Mark J. Kurth

Research output: Contribution to journal › Article

31 Citations (Scopus)

Abstract

Polymer-bound α-sulfonyl monocarbanions can be generated very effectively with dimsyl anion. The highly efficient and convenient protocols presented here report the preparation of α,β-unsaturated ketones and vinylaryl compounds using dimsyl anion to achieve the key solid-phase α-sulfonyl monocarbanion alkylation step.

Original languageEnglish (US)
Pages (from-to)2967-2970
Number of pages4
JournalTetrahedron Letters
Volume43
Issue number16
DOIs
StatePublished - Apr 15 2002

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Sulfones
Anions
Alkylation
Ketones
Polymers

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Dimsyl anion in the monoalkylation of solid-phase alkyl sulfones. / Cheng, Wei Chieh; Lin, Chu Chung; Kurth, Mark J.

In: Tetrahedron Letters, Vol. 43, No. 16, 15.04.2002, p. 2967-2970.

Research output: Contribution to journal › Article

Cheng, WC, Lin, CC & Kurth, MJ 2002, 'Dimsyl anion in the monoalkylation of solid-phase alkyl sulfones', Tetrahedron Letters, vol. 43, no. 16, pp. 2967-2970. https://doi.org/10.1016/S0040-4039(02)00423-9
Cheng WC, Lin CC, Kurth MJ. Dimsyl anion in the monoalkylation of solid-phase alkyl sulfones. Tetrahedron Letters. 2002 Apr 15;43(16):2967-2970. https://doi.org/10.1016/S0040-4039(02)00423-9
Cheng, Wei Chieh ; Lin, Chu Chung ; Kurth, Mark J. / Dimsyl anion in the monoalkylation of solid-phase alkyl sulfones. In: Tetrahedron Letters. 2002 ; Vol. 43, No. 16. pp. 2967-2970.
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