Dimsyl anion in the monoalkylation of solid-phase alkyl sulfones

Wei Chieh Cheng, Chu Chung Lin, Mark J. Kurth

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Polymer-bound α-sulfonyl monocarbanions can be generated very effectively with dimsyl anion. The highly efficient and convenient protocols presented here report the preparation of α,β-unsaturated ketones and vinylaryl compounds using dimsyl anion to achieve the key solid-phase α-sulfonyl monocarbanion alkylation step.

Original languageEnglish (US)
Pages (from-to)2967-2970
Number of pages4
JournalTetrahedron Letters
Volume43
Issue number16
DOIs
StatePublished - Apr 15 2002

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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