Dimethylsulphoxide-induced toxicity

Peter Mackinlay Yellowlees, C. Greenfield, N. McIntyre

Research output: Contribution to journal › Article

68 Citations (Scopus)

Abstract

Two elderly people were given intravenous infusions of dimethylsulphoxide (DMSO) as treatment for arthritis. One became seriously ill, the other remained well. Both had similar changes in aspartate transaminase, hydroxybutyrate dehydrogenase, and creatine kinase and evidence of haemolysis. This is the first report of serum enzyme changes and anaemia after intravenous DMSO in man.

Original languageEnglish (US)
Pages (from-to)1004-1006
Number of pages3
JournalLancet
Volume2
Issue number8202
StatePublished - 1980
Externally publishedYes

Fingerprint

Dimethyl Sulfoxide
Hydroxybutyrate Dehydrogenase
Creatine Kinase
Aspartate Aminotransferases
Hemolysis
Intravenous Infusions
Arthritis
Anemia
Enzymes
Serum
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Yellowlees, P. M., Greenfield, C., & McIntyre, N. (1980). Dimethylsulphoxide-induced toxicity. Lancet, 2(8202), 1004-1006.

Dimethylsulphoxide-induced toxicity. / Yellowlees, Peter Mackinlay; Greenfield, C.; McIntyre, N.

In: Lancet, Vol. 2, No. 8202, 1980, p. 1004-1006.

Research output: Contribution to journal › Article

Yellowlees, PM, Greenfield, C & McIntyre, N 1980, 'Dimethylsulphoxide-induced toxicity', Lancet, vol. 2, no. 8202, pp. 1004-1006.
Yellowlees PM, Greenfield C, McIntyre N. Dimethylsulphoxide-induced toxicity. Lancet. 1980;2(8202):1004-1006.
Yellowlees, Peter Mackinlay ; Greenfield, C. ; McIntyre, N. / Dimethylsulphoxide-induced toxicity. In: Lancet. 1980 ; Vol. 2, No. 8202. pp. 1004-1006.
@article{4513409c9e6a43afb1c9fe23663e28f3,
title = "Dimethylsulphoxide-induced toxicity",
abstract = "Two elderly people were given intravenous infusions of dimethylsulphoxide (DMSO) as treatment for arthritis. One became seriously ill, the other remained well. Both had similar changes in aspartate transaminase, hydroxybutyrate dehydrogenase, and creatine kinase and evidence of haemolysis. This is the first report of serum enzyme changes and anaemia after intravenous DMSO in man.",
author = "Yellowlees, {Peter Mackinlay} and C. Greenfield and N. McIntyre",
year = "1980",
language = "English (US)",
volume = "2",
pages = "1004--1006",
journal = "The Lancet",
issn = "0140-6736",
publisher = "Elsevier Limited",
number = "8202",

}

TY - JOUR

T1 - Dimethylsulphoxide-induced toxicity

AU - Yellowlees, Peter Mackinlay

AU - Greenfield, C.

AU - McIntyre, N.

PY - 1980

Y1 - 1980

N2 - Two elderly people were given intravenous infusions of dimethylsulphoxide (DMSO) as treatment for arthritis. One became seriously ill, the other remained well. Both had similar changes in aspartate transaminase, hydroxybutyrate dehydrogenase, and creatine kinase and evidence of haemolysis. This is the first report of serum enzyme changes and anaemia after intravenous DMSO in man.

AB - Two elderly people were given intravenous infusions of dimethylsulphoxide (DMSO) as treatment for arthritis. One became seriously ill, the other remained well. Both had similar changes in aspartate transaminase, hydroxybutyrate dehydrogenase, and creatine kinase and evidence of haemolysis. This is the first report of serum enzyme changes and anaemia after intravenous DMSO in man.

UR - http://www.scopus.com/inward/record.url?scp=0018968057&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018968057&partnerID=8YFLogxK

M3 - Article

C2 - 6107630

AN - SCOPUS:0018968057

VL - 2

SP - 1004

EP - 1006

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 8202

ER -

Access to Document