Dimethylsulphoxide-induced toxicity

Peter Mackinlay Yellowlees, C. Greenfield, N. McIntyre

Research output: Contribution to journalArticle

69 Scopus citations


Two elderly people were given intravenous infusions of dimethylsulphoxide (DMSO) as treatment for arthritis. One became seriously ill, the other remained well. Both had similar changes in aspartate transaminase, hydroxybutyrate dehydrogenase, and creatine kinase and evidence of haemolysis. This is the first report of serum enzyme changes and anaemia after intravenous DMSO in man.

Original languageEnglish (US)
Pages (from-to)1004-1006
Number of pages3
Issue number8202
StatePublished - 1980
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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    Yellowlees, P. M., Greenfield, C., & McIntyre, N. (1980). Dimethylsulphoxide-induced toxicity. Lancet, 2(8202), 1004-1006.