Dimensions of cognitive ability in dementia: Differential sensitivity to degree of impairment in Alzheimer's disease

Dan M Mungas, Roberta Wallace, Bruce R Reed

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

The purpose of this study was to identify dimensions of cognitive functioning in demented elderly persons and examine sensitivity of these dimensions to different degrees of cognitive impairment in Alzheimer's disease. Participants included 210 demented elderly patients and 89 normal controls. Principal components analysis of neuropsychological test scores for the demented patients yielded the following six components: (1) Memory/Learning, (2) Spatial/Nonverbal, (3) Verbal/Lexical Knowledge, (4) Verbal Fluency, (5) Visual Paired Associates, and (6) Verbal Attention Span. All dimensions discriminated among normal controls and three groups of patients with probable Alzheimer's disease defined by decreasing Mini-Mental State Exam scores. Differential sensitivity of cognitive dimensions was observed as a function of level of cognitive impairment.

Original languageEnglish (US)
Pages (from-to)129-142
Number of pages14
JournalClinical Neuropsychologist
Volume12
Issue number2
StatePublished - 1998

ASJC Scopus subject areas

  • Psychiatry and Mental health

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