TY - JOUR
T1 - Diffuse Idiopathic Skeletal Hyperostosis of the Spine
T2 - Pathophysiology, Diagnosis, and Management
AU - Le, Hai V.
AU - Wick, Joseph B.
AU - Van, Benjamin W.
AU - Klineberg, Eric O.
N1 - Publisher Copyright:
Copyright © 2021 by the American Academy of Orthopaedic Surgeons.
PY - 2021/12/15
Y1 - 2021/12/15
N2 - Diffuse idiopathic skeletal hyperostosis (DISH) is an ankylosing condition affecting up to 32.5% of the general cohort. Although often asymptomatic, affected individuals may present with back pain, stiffness, dysphagia, functional decline, and neurologic deficits. Radiographically, DISH is characterized by flowing ossifications along the anterior spine spanning ≥4 vertebral bodies. Although the etiology of DISH remains unknown, diabetes mellitus and other metabolic derangements are strongly associated with DISH. Importantly, spinal ankylosis in DISH predisposes patients to unstable spine fractures from low-energy trauma, and careful consideration must be taken in managing these patients. This article reviews the epidemiology and pathophysiology of DISH, and its clinical findings, diagnostic criteria, and management.
AB - Diffuse idiopathic skeletal hyperostosis (DISH) is an ankylosing condition affecting up to 32.5% of the general cohort. Although often asymptomatic, affected individuals may present with back pain, stiffness, dysphagia, functional decline, and neurologic deficits. Radiographically, DISH is characterized by flowing ossifications along the anterior spine spanning ≥4 vertebral bodies. Although the etiology of DISH remains unknown, diabetes mellitus and other metabolic derangements are strongly associated with DISH. Importantly, spinal ankylosis in DISH predisposes patients to unstable spine fractures from low-energy trauma, and careful consideration must be taken in managing these patients. This article reviews the epidemiology and pathophysiology of DISH, and its clinical findings, diagnostic criteria, and management.
UR - http://www.scopus.com/inward/record.url?scp=85122646320&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85122646320&partnerID=8YFLogxK
U2 - 10.5435/JAAOS-D-20-01344
DO - 10.5435/JAAOS-D-20-01344
M3 - Review article
C2 - 34559699
AN - SCOPUS:85122646320
VL - 29
SP - 1044
EP - 1051
JO - Journal of the American Academy of Orthopaedic Surgeons
JF - Journal of the American Academy of Orthopaedic Surgeons
SN - 1067-151X
IS - 24
ER -