Differential effect of hypoxia on meal size and meal frequency in the rat

D. D. Schnakenberg, P. M.B. Leung, Quinton Rogers

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Male rats (n=7, 250 g) were maintained in a vinyl glove box with free access to a 20% casein diet and water. Continuous recording balances (sensitivity 0.1 g) were used to monitor meal feeding behavior during a 3 day preliminary period (P) in air, 1 day of 12% O2 (H) exposure beginning at the onset of the 12 hr dark period, and the first day of recovery (R) in air. Daily water intake was also measured. Food consumption (X ± SEM) during (P), (H), and (R) was 21.5±0.6, 11.6±1.4 and 19.6±0.5 g/day, respectively and the water intake was 31.2±1.6, 10.1±2.3, and 37.1±1.2 ml/day, respectively. Expressed as a percentage of (P), the hypodipsic effect (32.4%) was relatively more severe than the hypophagic effect (54.0%). Postprandial criteria of greater than 10, 20, 30, and 40 min were used to calculate meal size and meal frequency (number of meals). Acute (H) exposure inhibited food consumption by reducing meal size, not meal frequency. However, the size of the first meal during (H) was not reduced. Meal feeding behavior during (R) did not differ from (P). The observed pattern of early termination of a given meal during hypoxia is remarkably similar to that observed during partial water restriction, suggesting that hypoxic hypophagia may, at least in part, be secondary to the hypodipsic effect of hypoxia.

Original languageEnglish (US)
JournalFederation Proceedings
Volume33
Issue number3 I
StatePublished - Jan 1 1974

Fingerprint

Meals
Feeding Behavior
Drinking
Air
Hypoxia
Food
Water
Caseins
Diet

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Differential effect of hypoxia on meal size and meal frequency in the rat. / Schnakenberg, D. D.; Leung, P. M.B.; Rogers, Quinton.

In: Federation Proceedings, Vol. 33, No. 3 I, 01.01.1974.

Research output: Contribution to journalArticle

@article{e16c8676e57d41c7b16c0cc71c391f18,
title = "Differential effect of hypoxia on meal size and meal frequency in the rat",
abstract = "Male rats (n=7, 250 g) were maintained in a vinyl glove box with free access to a 20{\%} casein diet and water. Continuous recording balances (sensitivity 0.1 g) were used to monitor meal feeding behavior during a 3 day preliminary period (P) in air, 1 day of 12{\%} O2 (H) exposure beginning at the onset of the 12 hr dark period, and the first day of recovery (R) in air. Daily water intake was also measured. Food consumption (X ± SEM) during (P), (H), and (R) was 21.5±0.6, 11.6±1.4 and 19.6±0.5 g/day, respectively and the water intake was 31.2±1.6, 10.1±2.3, and 37.1±1.2 ml/day, respectively. Expressed as a percentage of (P), the hypodipsic effect (32.4{\%}) was relatively more severe than the hypophagic effect (54.0{\%}). Postprandial criteria of greater than 10, 20, 30, and 40 min were used to calculate meal size and meal frequency (number of meals). Acute (H) exposure inhibited food consumption by reducing meal size, not meal frequency. However, the size of the first meal during (H) was not reduced. Meal feeding behavior during (R) did not differ from (P). The observed pattern of early termination of a given meal during hypoxia is remarkably similar to that observed during partial water restriction, suggesting that hypoxic hypophagia may, at least in part, be secondary to the hypodipsic effect of hypoxia.",
author = "Schnakenberg, {D. D.} and Leung, {P. M.B.} and Quinton Rogers",
year = "1974",
month = "1",
day = "1",
language = "English (US)",
volume = "33",
journal = "Federation Proceedings",
issn = "0014-9446",
number = "3 I",

}

TY - JOUR

T1 - Differential effect of hypoxia on meal size and meal frequency in the rat

AU - Schnakenberg, D. D.

AU - Leung, P. M.B.

AU - Rogers, Quinton

PY - 1974/1/1

Y1 - 1974/1/1

N2 - Male rats (n=7, 250 g) were maintained in a vinyl glove box with free access to a 20% casein diet and water. Continuous recording balances (sensitivity 0.1 g) were used to monitor meal feeding behavior during a 3 day preliminary period (P) in air, 1 day of 12% O2 (H) exposure beginning at the onset of the 12 hr dark period, and the first day of recovery (R) in air. Daily water intake was also measured. Food consumption (X ± SEM) during (P), (H), and (R) was 21.5±0.6, 11.6±1.4 and 19.6±0.5 g/day, respectively and the water intake was 31.2±1.6, 10.1±2.3, and 37.1±1.2 ml/day, respectively. Expressed as a percentage of (P), the hypodipsic effect (32.4%) was relatively more severe than the hypophagic effect (54.0%). Postprandial criteria of greater than 10, 20, 30, and 40 min were used to calculate meal size and meal frequency (number of meals). Acute (H) exposure inhibited food consumption by reducing meal size, not meal frequency. However, the size of the first meal during (H) was not reduced. Meal feeding behavior during (R) did not differ from (P). The observed pattern of early termination of a given meal during hypoxia is remarkably similar to that observed during partial water restriction, suggesting that hypoxic hypophagia may, at least in part, be secondary to the hypodipsic effect of hypoxia.

AB - Male rats (n=7, 250 g) were maintained in a vinyl glove box with free access to a 20% casein diet and water. Continuous recording balances (sensitivity 0.1 g) were used to monitor meal feeding behavior during a 3 day preliminary period (P) in air, 1 day of 12% O2 (H) exposure beginning at the onset of the 12 hr dark period, and the first day of recovery (R) in air. Daily water intake was also measured. Food consumption (X ± SEM) during (P), (H), and (R) was 21.5±0.6, 11.6±1.4 and 19.6±0.5 g/day, respectively and the water intake was 31.2±1.6, 10.1±2.3, and 37.1±1.2 ml/day, respectively. Expressed as a percentage of (P), the hypodipsic effect (32.4%) was relatively more severe than the hypophagic effect (54.0%). Postprandial criteria of greater than 10, 20, 30, and 40 min were used to calculate meal size and meal frequency (number of meals). Acute (H) exposure inhibited food consumption by reducing meal size, not meal frequency. However, the size of the first meal during (H) was not reduced. Meal feeding behavior during (R) did not differ from (P). The observed pattern of early termination of a given meal during hypoxia is remarkably similar to that observed during partial water restriction, suggesting that hypoxic hypophagia may, at least in part, be secondary to the hypodipsic effect of hypoxia.

UR - http://www.scopus.com/inward/record.url?scp=17544394499&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=17544394499&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:17544394499

VL - 33

JO - Federation Proceedings

JF - Federation Proceedings

SN - 0014-9446

IS - 3 I

ER -