Differences in treatment patterns for localized breast carcinoma among Asian/Pacific Islander women

Angela W. Prehn, Barbara Topol, Susan L Stewart, Sally L. Glaser, Lilia O'Connor, Dee W. West

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

BACKGROUND. Many studies have examined racial/ethnic differences in treatment for localized breast carcinoma, but to the authors' knowledge few have included Asian/Pacific Islander (API) women. METHODS. The population-based study included API and non-Hispanic white women diagnosed with localized invasive breast carcinoma in the Greater San Francisco Bay Area during 1994 (n = 1772). Multiple logistic regression was used to assess the association between race/ethnicity and type of surgery, radiation therapy following breast-conserving surgery (BCS), and hormone therapy for estrogen receptor-positive tumors while adjusting for demographic, medical, and census block-group socioeconomic characteristics. RESULTS. API women were significantly more likely to undergo mastectomies than white women (58% vs. 42%). This difference remained for Chinese and Filipino women after multivariate adjustment (odds ratio vs. whites [OR] = 2.4, 95% confidence interval [95% CI] = 1.4-4.2; OR [95%CI] = 1.8[1.0-3.1], respectively). Chinese women were also more likely than white women to not receive adjuvant therapy, be it radiation after BCS or hormone therapy for estrogen receptor-positive disease. Other API women did not differ from white women in adjuvant therapy use. CONCLUSIONS. This population-based study identified differences in treatment for localized breast carcinoma by race/ethnicity that were not explained by differences in demographic, medical, or socioeconomic characteristics. These results underscore the importance of looking at treatment patterns separately for API subgroups and support the need for research into cultural differences that may influence breast carcinoma treatment choices.

Original languageEnglish (US)
Pages (from-to)2268-2275
Number of pages8
JournalCancer
Volume95
Issue number11
DOIs
StatePublished - Dec 1 2002
Externally publishedYes

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Breast Neoplasms
Therapeutics
Segmental Mastectomy
Estrogen Receptors
Demography
Hormones
San Francisco
Mastectomy
Censuses
Population
Radiotherapy
Logistic Models
Odds Ratio
Confidence Intervals
Radiation
Research
Neoplasms

Keywords

  • Asians
  • Breast neoplasms
  • Breast-conserving surgery (BCS)
  • Epidemiology
  • Epidemiology, and End Results (SEER)
  • Hormone therapy
  • Pacific Islanders
  • Radiation therapy
  • Surveillance
  • Treatment

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Differences in treatment patterns for localized breast carcinoma among Asian/Pacific Islander women. / Prehn, Angela W.; Topol, Barbara; Stewart, Susan L; Glaser, Sally L.; O'Connor, Lilia; West, Dee W.

In: Cancer, Vol. 95, No. 11, 01.12.2002, p. 2268-2275.

Research output: Contribution to journalArticle

Prehn, Angela W. ; Topol, Barbara ; Stewart, Susan L ; Glaser, Sally L. ; O'Connor, Lilia ; West, Dee W. / Differences in treatment patterns for localized breast carcinoma among Asian/Pacific Islander women. In: Cancer. 2002 ; Vol. 95, No. 11. pp. 2268-2275.
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abstract = "BACKGROUND. Many studies have examined racial/ethnic differences in treatment for localized breast carcinoma, but to the authors' knowledge few have included Asian/Pacific Islander (API) women. METHODS. The population-based study included API and non-Hispanic white women diagnosed with localized invasive breast carcinoma in the Greater San Francisco Bay Area during 1994 (n = 1772). Multiple logistic regression was used to assess the association between race/ethnicity and type of surgery, radiation therapy following breast-conserving surgery (BCS), and hormone therapy for estrogen receptor-positive tumors while adjusting for demographic, medical, and census block-group socioeconomic characteristics. RESULTS. API women were significantly more likely to undergo mastectomies than white women (58{\%} vs. 42{\%}). This difference remained for Chinese and Filipino women after multivariate adjustment (odds ratio vs. whites [OR] = 2.4, 95{\%} confidence interval [95{\%} CI] = 1.4-4.2; OR [95{\%}CI] = 1.8[1.0-3.1], respectively). Chinese women were also more likely than white women to not receive adjuvant therapy, be it radiation after BCS or hormone therapy for estrogen receptor-positive disease. Other API women did not differ from white women in adjuvant therapy use. CONCLUSIONS. This population-based study identified differences in treatment for localized breast carcinoma by race/ethnicity that were not explained by differences in demographic, medical, or socioeconomic characteristics. These results underscore the importance of looking at treatment patterns separately for API subgroups and support the need for research into cultural differences that may influence breast carcinoma treatment choices.",
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AU - Prehn, Angela W.

AU - Topol, Barbara

AU - Stewart, Susan L

AU - Glaser, Sally L.

AU - O'Connor, Lilia

AU - West, Dee W.

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N2 - BACKGROUND. Many studies have examined racial/ethnic differences in treatment for localized breast carcinoma, but to the authors' knowledge few have included Asian/Pacific Islander (API) women. METHODS. The population-based study included API and non-Hispanic white women diagnosed with localized invasive breast carcinoma in the Greater San Francisco Bay Area during 1994 (n = 1772). Multiple logistic regression was used to assess the association between race/ethnicity and type of surgery, radiation therapy following breast-conserving surgery (BCS), and hormone therapy for estrogen receptor-positive tumors while adjusting for demographic, medical, and census block-group socioeconomic characteristics. RESULTS. API women were significantly more likely to undergo mastectomies than white women (58% vs. 42%). This difference remained for Chinese and Filipino women after multivariate adjustment (odds ratio vs. whites [OR] = 2.4, 95% confidence interval [95% CI] = 1.4-4.2; OR [95%CI] = 1.8[1.0-3.1], respectively). Chinese women were also more likely than white women to not receive adjuvant therapy, be it radiation after BCS or hormone therapy for estrogen receptor-positive disease. Other API women did not differ from white women in adjuvant therapy use. CONCLUSIONS. This population-based study identified differences in treatment for localized breast carcinoma by race/ethnicity that were not explained by differences in demographic, medical, or socioeconomic characteristics. These results underscore the importance of looking at treatment patterns separately for API subgroups and support the need for research into cultural differences that may influence breast carcinoma treatment choices.

AB - BACKGROUND. Many studies have examined racial/ethnic differences in treatment for localized breast carcinoma, but to the authors' knowledge few have included Asian/Pacific Islander (API) women. METHODS. The population-based study included API and non-Hispanic white women diagnosed with localized invasive breast carcinoma in the Greater San Francisco Bay Area during 1994 (n = 1772). Multiple logistic regression was used to assess the association between race/ethnicity and type of surgery, radiation therapy following breast-conserving surgery (BCS), and hormone therapy for estrogen receptor-positive tumors while adjusting for demographic, medical, and census block-group socioeconomic characteristics. RESULTS. API women were significantly more likely to undergo mastectomies than white women (58% vs. 42%). This difference remained for Chinese and Filipino women after multivariate adjustment (odds ratio vs. whites [OR] = 2.4, 95% confidence interval [95% CI] = 1.4-4.2; OR [95%CI] = 1.8[1.0-3.1], respectively). Chinese women were also more likely than white women to not receive adjuvant therapy, be it radiation after BCS or hormone therapy for estrogen receptor-positive disease. Other API women did not differ from white women in adjuvant therapy use. CONCLUSIONS. This population-based study identified differences in treatment for localized breast carcinoma by race/ethnicity that were not explained by differences in demographic, medical, or socioeconomic characteristics. These results underscore the importance of looking at treatment patterns separately for API subgroups and support the need for research into cultural differences that may influence breast carcinoma treatment choices.

KW - Asians

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KW - Pacific Islanders

KW - Radiation therapy

KW - Surveillance

KW - Treatment

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