Differences in marital status and mortality by race/ethnicity and nativity among California cancer patients

María Elena Martínez, Kristin Anderson, James D. Murphy, Susan Hurley, Alison J. Canchola, Theresa H Keegan, Iona Cheng, Christina A. Clarke, Sally L. Glaser, Scarlett L. Gomez

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

BACKGROUND It has been observed that married cancer patients have lower mortality rates than unmarried patients, but data for different racial/ethnic groups are scarce. The authors examined the risk of overall mortality associated with marital status across racial/ethnic groups and sex in data from the California Cancer Registry. METHODS California Cancer Registry data for all first primary invasive cancers diagnosed from 2000 through 2009 for the 10 most common sites of cancer-related death for non-Hispanic whites (NHWs), blacks, Asians/Pacific Islanders (APIs), and Hispanics were used to estimate multivariable hazard ratios (HRs) and 95% confidence intervals (CIs) for marital status in relation to overall mortality by race/ethnicity and sex. The study cohort included 393,470 male and 389,697 female cancer patients and 204,007 and 182,600 deaths from all causes, respectively, through December 31, 2012. RESULTS All-cause mortality was higher in unmarried patients than in married patients, but there was significant variation by race/ethnicity. Adjusted HRs (95% CIs) ranged from 1.24 (95% CI, 1.23-1.26) in NHWs to 1.11 (95% CI, 1.07-1.15) in APIs among males and from 1.17 (95% CI, 1.15-1.18) in NHWs to 1.07 (95% CI, 1.04-1.11) in APIs among females. All-cause mortality associated with unmarried status compared with married status was higher in US-born API and Hispanic men and women relative to their foreign-born counterparts. CONCLUSIONS For patients who have the cancers that contribute most to mortality, being unmarried is associated with worse overall survival compared with being married, with up to 24% higher mortality among NHW males but only 6% higher mortality among foreign-born Hispanic and API females. Future research should pursue the identification of factors underlying these associations to inform targeted interventions for unmarried cancer patients.

Original languageEnglish (US)
Pages (from-to)1570-1578
Number of pages9
JournalCancer
Volume122
Issue number10
DOIs
StatePublished - May 15 2016

Keywords

  • marriage
  • mortality
  • nativity
  • neighborhood socioeconomic status
  • race/ethnicity

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Martínez, M. E., Anderson, K., Murphy, J. D., Hurley, S., Canchola, A. J., Keegan, T. H., Cheng, I., Clarke, C. A., Glaser, S. L., & Gomez, S. L. (2016). Differences in marital status and mortality by race/ethnicity and nativity among California cancer patients. Cancer, 122(10), 1570-1578. https://doi.org/10.1002/cncr.29886