Dietary predictors of urinary environmental biomarkers in young girls, BCERP, 2004-7

Nancy Mervish, Kathleen J. McGovern, Susan L. Teitelbaum, Susan M. Pinney, Gayle C. Windham, Frank M. Biro, Lawrence H. Kushi, Manori J. Silva, Xiaoyun Ye, Antonia M. Calafat, Mary S. Wolff

Research output: Contribution to journalArticle

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Abstract

Background: Exposures of children to phthalates, parabens, and bisphenol-A (BPA) are of concern because of their hormonal potential. These agents are found in a wide range of foods and packaging. We investigated whether intake of certain foods predict exposures to these chemicals in young girls. Methods: Among 1101 girls (6-8 years at enrollment) from the Breast Cancer and Environment Research Program (BCERP) study, we measured urinary exposure biomarkers for phthalates, parabens, and BPA and assessed dietary intake using 24-h recall 2-4 times. We examined the average daily servings of major and minor food groups categorized as 0 to <0.5, 0.5 to <1 and ≥1 servings per day. Items included dairy, eggs, fats, fish, fruit, single grains, meat, non-poultry meats, pasta, poultry and vegetables. Covariate-adjusted least squares geometric means and 95% confidence intervals of creatinine-corrected phthalate and phenol metabolite concentrations in urine were calculated in relation to food intake. Results: Grains, flour and dry mixes and total fish consumption were positively associated with BPA and the sum of four di-2-ethylhexylphthalate (DEHP) urinary metabolite concentrations. Non-fresh vegetables and poultry were both positively associated with BPA and paraben urinary concentrations. Fats, oils and poultry consumption were positively associated with BPA. Whole-fat dairy consumption was associated with σDEHP. Conclusions: Some foods may contribute to child exposures to certain chemicals, and this may constitute modifiable means to reduce these environmental exposures.

Original languageEnglish (US)
Pages (from-to)12-19
Number of pages8
JournalEnvironmental Research
Volume133
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Biomarkers
research program
Parabens
biomarker
cancer
Poultry
Breast Neoplasms
phthalate
poultry
Diethylhexyl Phthalate
fat
Research
Dairies
food
Meats
Fats
Vegetables
Metabolites
meat
Meat

Keywords

  • Biomarkers
  • Bisphenol A
  • Endocrine disruptors
  • Parabens
  • Phthalates

ASJC Scopus subject areas

  • Environmental Science(all)
  • Biochemistry

Cite this

Mervish, N., McGovern, K. J., Teitelbaum, S. L., Pinney, S. M., Windham, G. C., Biro, F. M., ... Wolff, M. S. (2014). Dietary predictors of urinary environmental biomarkers in young girls, BCERP, 2004-7. Environmental Research, 133, 12-19. https://doi.org/10.1016/j.envres.2014.04.040

Dietary predictors of urinary environmental biomarkers in young girls, BCERP, 2004-7. / Mervish, Nancy; McGovern, Kathleen J.; Teitelbaum, Susan L.; Pinney, Susan M.; Windham, Gayle C.; Biro, Frank M.; Kushi, Lawrence H.; Silva, Manori J.; Ye, Xiaoyun; Calafat, Antonia M.; Wolff, Mary S.

In: Environmental Research, Vol. 133, 2014, p. 12-19.

Research output: Contribution to journalArticle

Mervish, N, McGovern, KJ, Teitelbaum, SL, Pinney, SM, Windham, GC, Biro, FM, Kushi, LH, Silva, MJ, Ye, X, Calafat, AM & Wolff, MS 2014, 'Dietary predictors of urinary environmental biomarkers in young girls, BCERP, 2004-7', Environmental Research, vol. 133, pp. 12-19. https://doi.org/10.1016/j.envres.2014.04.040
Mervish, Nancy ; McGovern, Kathleen J. ; Teitelbaum, Susan L. ; Pinney, Susan M. ; Windham, Gayle C. ; Biro, Frank M. ; Kushi, Lawrence H. ; Silva, Manori J. ; Ye, Xiaoyun ; Calafat, Antonia M. ; Wolff, Mary S. / Dietary predictors of urinary environmental biomarkers in young girls, BCERP, 2004-7. In: Environmental Research. 2014 ; Vol. 133. pp. 12-19.
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abstract = "Background: Exposures of children to phthalates, parabens, and bisphenol-A (BPA) are of concern because of their hormonal potential. These agents are found in a wide range of foods and packaging. We investigated whether intake of certain foods predict exposures to these chemicals in young girls. Methods: Among 1101 girls (6-8 years at enrollment) from the Breast Cancer and Environment Research Program (BCERP) study, we measured urinary exposure biomarkers for phthalates, parabens, and BPA and assessed dietary intake using 24-h recall 2-4 times. We examined the average daily servings of major and minor food groups categorized as 0 to <0.5, 0.5 to <1 and ≥1 servings per day. Items included dairy, eggs, fats, fish, fruit, single grains, meat, non-poultry meats, pasta, poultry and vegetables. Covariate-adjusted least squares geometric means and 95{\%} confidence intervals of creatinine-corrected phthalate and phenol metabolite concentrations in urine were calculated in relation to food intake. Results: Grains, flour and dry mixes and total fish consumption were positively associated with BPA and the sum of four di-2-ethylhexylphthalate (DEHP) urinary metabolite concentrations. Non-fresh vegetables and poultry were both positively associated with BPA and paraben urinary concentrations. Fats, oils and poultry consumption were positively associated with BPA. Whole-fat dairy consumption was associated with σDEHP. Conclusions: Some foods may contribute to child exposures to certain chemicals, and this may constitute modifiable means to reduce these environmental exposures.",
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AU - Mervish, Nancy

AU - McGovern, Kathleen J.

AU - Teitelbaum, Susan L.

AU - Pinney, Susan M.

AU - Windham, Gayle C.

AU - Biro, Frank M.

AU - Kushi, Lawrence H.

AU - Silva, Manori J.

AU - Ye, Xiaoyun

AU - Calafat, Antonia M.

AU - Wolff, Mary S.

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N2 - Background: Exposures of children to phthalates, parabens, and bisphenol-A (BPA) are of concern because of their hormonal potential. These agents are found in a wide range of foods and packaging. We investigated whether intake of certain foods predict exposures to these chemicals in young girls. Methods: Among 1101 girls (6-8 years at enrollment) from the Breast Cancer and Environment Research Program (BCERP) study, we measured urinary exposure biomarkers for phthalates, parabens, and BPA and assessed dietary intake using 24-h recall 2-4 times. We examined the average daily servings of major and minor food groups categorized as 0 to <0.5, 0.5 to <1 and ≥1 servings per day. Items included dairy, eggs, fats, fish, fruit, single grains, meat, non-poultry meats, pasta, poultry and vegetables. Covariate-adjusted least squares geometric means and 95% confidence intervals of creatinine-corrected phthalate and phenol metabolite concentrations in urine were calculated in relation to food intake. Results: Grains, flour and dry mixes and total fish consumption were positively associated with BPA and the sum of four di-2-ethylhexylphthalate (DEHP) urinary metabolite concentrations. Non-fresh vegetables and poultry were both positively associated with BPA and paraben urinary concentrations. Fats, oils and poultry consumption were positively associated with BPA. Whole-fat dairy consumption was associated with σDEHP. Conclusions: Some foods may contribute to child exposures to certain chemicals, and this may constitute modifiable means to reduce these environmental exposures.

AB - Background: Exposures of children to phthalates, parabens, and bisphenol-A (BPA) are of concern because of their hormonal potential. These agents are found in a wide range of foods and packaging. We investigated whether intake of certain foods predict exposures to these chemicals in young girls. Methods: Among 1101 girls (6-8 years at enrollment) from the Breast Cancer and Environment Research Program (BCERP) study, we measured urinary exposure biomarkers for phthalates, parabens, and BPA and assessed dietary intake using 24-h recall 2-4 times. We examined the average daily servings of major and minor food groups categorized as 0 to <0.5, 0.5 to <1 and ≥1 servings per day. Items included dairy, eggs, fats, fish, fruit, single grains, meat, non-poultry meats, pasta, poultry and vegetables. Covariate-adjusted least squares geometric means and 95% confidence intervals of creatinine-corrected phthalate and phenol metabolite concentrations in urine were calculated in relation to food intake. Results: Grains, flour and dry mixes and total fish consumption were positively associated with BPA and the sum of four di-2-ethylhexylphthalate (DEHP) urinary metabolite concentrations. Non-fresh vegetables and poultry were both positively associated with BPA and paraben urinary concentrations. Fats, oils and poultry consumption were positively associated with BPA. Whole-fat dairy consumption was associated with σDEHP. Conclusions: Some foods may contribute to child exposures to certain chemicals, and this may constitute modifiable means to reduce these environmental exposures.

KW - Biomarkers

KW - Bisphenol A

KW - Endocrine disruptors

KW - Parabens

KW - Phthalates

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