Dietary cysteic acid serves as a precursor of taurine for cats

S. E. Edgar, M. A. Hickman, M. M. Marsden, James Morris, Quinton Rogers

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11 Citations (Scopus)

Abstract

The ability of cats to use dietary cysteic acid as a precursor for taurine was examined. For 39 wk, six groups of four specific-pathogen-free cats each were fed purified diets that provided either 1.25 g taurine or 0, 1.0, 2.0, 10 or 20 g cysteic acid/kg diet. Concentrations of taurine in plasma and whole blood were measured weekly for 13 wk and monthly until 39 wk. Muscle concentrations of taurine at 12 wk were measured on a biopsy sample of the semitendinosus muscle. Fecal and urinary excretions of taurine and cysteic acid at 17 wk were measured. Concentrations of taurine in plasma and whole blood were linearly and positively correlated with cysteic acid in the diet (r2 = 0.88). Urinary taurine, a major route of excess taurine excretion, was positively correlated with the cysteic acid concentration of the diet (r2 = 0.94). Muscle and whole-blood taurine concentrations were also positively correlated (r2 = 0.96) with dietary cysteic acid concentration. Gross and histopathological examinations were performed on cats fed diets containing 20 g cysteic acid/kg diet. No adverse gross clinical signs were observed in cats fed any diets containing cysteic acid; minor histopathologic changes of the pancreas and thyroid were found in three of four cats fed 20 g cysteic acid/kg diet. Results suggest that cats are able to use dietary cysteic acid as a precursor for taurine biosynthesis.

Original languageEnglish (US)
Pages (from-to)103-109
Number of pages7
JournalJournal of Nutrition
Volume124
Issue number1
StatePublished - Jan 1 1994

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Cysteic Acid
Taurine
Cats
Diet
Muscles
Specific Pathogen-Free Organisms
Pancreas
Thyroid Gland

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Edgar, S. E., Hickman, M. A., Marsden, M. M., Morris, J., & Rogers, Q. (1994). Dietary cysteic acid serves as a precursor of taurine for cats. Journal of Nutrition, 124(1), 103-109.

Dietary cysteic acid serves as a precursor of taurine for cats. / Edgar, S. E.; Hickman, M. A.; Marsden, M. M.; Morris, James; Rogers, Quinton.

In: Journal of Nutrition, Vol. 124, No. 1, 01.01.1994, p. 103-109.

Research output: Contribution to journalArticle

Edgar, SE, Hickman, MA, Marsden, MM, Morris, J & Rogers, Q 1994, 'Dietary cysteic acid serves as a precursor of taurine for cats', Journal of Nutrition, vol. 124, no. 1, pp. 103-109.
Edgar, S. E. ; Hickman, M. A. ; Marsden, M. M. ; Morris, James ; Rogers, Quinton. / Dietary cysteic acid serves as a precursor of taurine for cats. In: Journal of Nutrition. 1994 ; Vol. 124, No. 1. pp. 103-109.
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