Dietary and anthropometric determinants of plasma lipoproteins during a long-term low-fat diet in healthy women

Siddika E Karakas, Silvana Martino, Paik Nyon Kim, Sheila Khilnani, Allison Boomer, Janice Depper, Bruce A. Reading, Lance K. Heilbrun

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

Long-term (1 y) effects of dietary fat intake on lipoprotein metabolism were determined in 72 healthy women receiving either a 15%-fat diet (n = 34) or usual diet (n = 38). Every three months food records, weight, waist-hip ratio (W:H), percent body fat, fasting plasma triglyceride, cholesterol (C), high-density-lipoprotein cholesterol (HDL-C), HDL2-C, and HDL3-C; apolipoprotein B and A-I, and postheparin lipoprotein lipase (LPL) and hepatic triglyceride lipase activities were determined. In one year, the low-fat-diet (LFD) group had 17% and the nonintervention-diet group had 36% dietary fat. The LFD group showed decreases in cholesterol: 7% TC, 13% low-density lipoprotein (LDL), and 8% HDL. Apolipoprotein A-I, decreased early. Apolipoprotein B did not change. Plasma triglyceride correlated with weight. Percent body fat and W:H correlated with the total and LDL-C. Changes in HDL-C and/or HDL2-C and LPL correlated directly with the changes in dietary fat and inversely with dietary carbohydrate. Changes in total-C or LDL-C correlated with the changes in weight and W:H, but not with the changes in nutrient intake.

Original languageEnglish (US)
Pages (from-to)146-153
Number of pages8
JournalAmerican Journal of Clinical Nutrition
Volume57
Issue number2
StatePublished - Feb 1993

Fingerprint

HDL2 Lipoprotein
Fat-Restricted Diet
Waist-Hip Ratio
low fat diet
waist
Dietary Fats
low density lipoprotein
hips
LDL Lipoproteins
lipoproteins
Lipoproteins
apolipoprotein B
lipoprotein lipase
Lipoprotein Lipase
Apolipoprotein A-I
Apolipoproteins B
Diet
high density lipoprotein cholesterol
Weights and Measures
dietary fat

Keywords

  • Lipases
  • Lipoproteins
  • Low-fat diet
  • Nutrients
  • Women

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)

Cite this

Karakas, S. E., Martino, S., Kim, P. N., Khilnani, S., Boomer, A., Depper, J., ... Heilbrun, L. K. (1993). Dietary and anthropometric determinants of plasma lipoproteins during a long-term low-fat diet in healthy women. American Journal of Clinical Nutrition, 57(2), 146-153.

Dietary and anthropometric determinants of plasma lipoproteins during a long-term low-fat diet in healthy women. / Karakas, Siddika E; Martino, Silvana; Kim, Paik Nyon; Khilnani, Sheila; Boomer, Allison; Depper, Janice; Reading, Bruce A.; Heilbrun, Lance K.

In: American Journal of Clinical Nutrition, Vol. 57, No. 2, 02.1993, p. 146-153.

Research output: Contribution to journalArticle

Karakas, SE, Martino, S, Kim, PN, Khilnani, S, Boomer, A, Depper, J, Reading, BA & Heilbrun, LK 1993, 'Dietary and anthropometric determinants of plasma lipoproteins during a long-term low-fat diet in healthy women', American Journal of Clinical Nutrition, vol. 57, no. 2, pp. 146-153.
Karakas, Siddika E ; Martino, Silvana ; Kim, Paik Nyon ; Khilnani, Sheila ; Boomer, Allison ; Depper, Janice ; Reading, Bruce A. ; Heilbrun, Lance K. / Dietary and anthropometric determinants of plasma lipoproteins during a long-term low-fat diet in healthy women. In: American Journal of Clinical Nutrition. 1993 ; Vol. 57, No. 2. pp. 146-153.
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