Abstract
Exploiting 1,3-dipolar cycloaddition and urea → hydantoin cyclization transformations, novel spiro-[cyclopenta[d]isoxazole-4'5-imidazolindine' heterocycles of generalized structure I have been prepared. The 1-amino-3- cyclopentenecarboxylate precursor II was prepared from a suitably activated/protected derivative of glycine and the bis-alkylating agent cis- 1,4-dichloro-2-butene.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 113-117 |
| Number of pages | 5 |
| Journal | Journal of Organic Chemistry |
| Volume | 63 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1998 |
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ASJC Scopus subject areas
- Organic Chemistry
Cite this
Diastereoselective synthesis of cyclopentanoids with hydantoin and isoxazoline substituents. / Park, Kyung Ho; Olmstead, Marilyn M.; Kurth, Mark J.
In: Journal of Organic Chemistry, Vol. 63, No. 1, 1998, p. 113-117.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Diastereoselective synthesis of cyclopentanoids with hydantoin and isoxazoline substituents
AU - Park, Kyung Ho
AU - Olmstead, Marilyn M.
AU - Kurth, Mark J.
PY - 1998
Y1 - 1998
N2 - Exploiting 1,3-dipolar cycloaddition and urea → hydantoin cyclization transformations, novel spiro-[cyclopenta[d]isoxazole-4'5-imidazolindine' heterocycles of generalized structure I have been prepared. The 1-amino-3- cyclopentenecarboxylate precursor II was prepared from a suitably activated/protected derivative of glycine and the bis-alkylating agent cis- 1,4-dichloro-2-butene.
AB - Exploiting 1,3-dipolar cycloaddition and urea → hydantoin cyclization transformations, novel spiro-[cyclopenta[d]isoxazole-4'5-imidazolindine' heterocycles of generalized structure I have been prepared. The 1-amino-3- cyclopentenecarboxylate precursor II was prepared from a suitably activated/protected derivative of glycine and the bis-alkylating agent cis- 1,4-dichloro-2-butene.
UR - http://www.scopus.com/inward/record.url?scp=0031907040&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031907040&partnerID=8YFLogxK
U2 - 10.1021/jo9714831
DO - 10.1021/jo9714831
M3 - Article
AN - SCOPUS:0031907040
VL - 63
SP - 113
EP - 117
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
SN - 0022-3263
IS - 1
ER -