Abstract
Exploiting 1,3-dipolar cycloaddition and urea → hydantoin cyclization transformations, novel spiro-[cyclopenta[d]isoxazole-4'5-imidazolindine' heterocycles of generalized structure I have been prepared. The 1-amino-3- cyclopentenecarboxylate precursor II was prepared from a suitably activated/protected derivative of glycine and the bis-alkylating agent cis- 1,4-dichloro-2-butene.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 113-117 |
| Number of pages | 5 |
| Journal | Journal of Organic Chemistry |
| Volume | 63 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1998 |
ASJC Scopus subject areas
- Organic Chemistry
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Cite this
Park, K. H., Olmstead, M. M., & Kurth, M. J. (1998). Diastereoselective synthesis of cyclopentanoids with hydantoin and isoxazoline substituents. Journal of Organic Chemistry, 63(1), 113-117. https://doi.org/10.1021/jo9714831