Abstract
Exploiting 1,3-dipolar cycloaddition and urea → hydantoin cyclization transformations, novel spiro-[cyclopenta[d]isoxazole-4'5-imidazolindine' heterocycles of generalized structure I have been prepared. The 1-amino-3- cyclopentenecarboxylate precursor II was prepared from a suitably activated/protected derivative of glycine and the bis-alkylating agent cis- 1,4-dichloro-2-butene.
Original language | English (US) |
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Pages (from-to) | 113-117 |
Number of pages | 5 |
Journal | Journal of Organic Chemistry |
Volume | 63 |
Issue number | 1 |
DOIs | |
State | Published - 1998 |
ASJC Scopus subject areas
- Organic Chemistry