Abstract
Six cirrhotic patients with intractable ascites had coexisting renal insufficiency. Dialytic ultrafiltration of ascitic fluid by hemofilter was attempted in these patients for symptomatic relief. The hemofilter removes fluid and substances with a molecular weight less than 50,000 daltons and the concentrated ascitic fluid was reinfused into the peritoneal cavity after ultrafiltration. A transient increase in urine output (p<0.01), urinary sodium excretion (p<0.01), and endogenous creatinine clearance (p<0.02) was noted and the plasma creatinine levels had remained stable for more than 4 months after the procedure. Our study suggests that dialytic ultrafiltration of ascites by hemofilter is a safe method in the management of patients with refractory ascites and renal insufficiency.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 665-668 |
| Number of pages | 4 |
| Journal | American Journal of Gastroenterology |
| Volume | 82 |
| Issue number | 7 |
| State | Published - 1987 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Gastroenterology
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Dialytic ultrafiltration by hemofilter in treatment of patients with refractory ascites and renal insufficiency. / Lai, K. N.; Leung, Joseph; Vallance-Owen, J.
In: American Journal of Gastroenterology, Vol. 82, No. 7, 1987, p. 665-668.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Dialytic ultrafiltration by hemofilter in treatment of patients with refractory ascites and renal insufficiency
AU - Lai, K. N.
AU - Leung, Joseph
AU - Vallance-Owen, J.
PY - 1987
Y1 - 1987
N2 - Six cirrhotic patients with intractable ascites had coexisting renal insufficiency. Dialytic ultrafiltration of ascitic fluid by hemofilter was attempted in these patients for symptomatic relief. The hemofilter removes fluid and substances with a molecular weight less than 50,000 daltons and the concentrated ascitic fluid was reinfused into the peritoneal cavity after ultrafiltration. A transient increase in urine output (p<0.01), urinary sodium excretion (p<0.01), and endogenous creatinine clearance (p<0.02) was noted and the plasma creatinine levels had remained stable for more than 4 months after the procedure. Our study suggests that dialytic ultrafiltration of ascites by hemofilter is a safe method in the management of patients with refractory ascites and renal insufficiency.
AB - Six cirrhotic patients with intractable ascites had coexisting renal insufficiency. Dialytic ultrafiltration of ascitic fluid by hemofilter was attempted in these patients for symptomatic relief. The hemofilter removes fluid and substances with a molecular weight less than 50,000 daltons and the concentrated ascitic fluid was reinfused into the peritoneal cavity after ultrafiltration. A transient increase in urine output (p<0.01), urinary sodium excretion (p<0.01), and endogenous creatinine clearance (p<0.02) was noted and the plasma creatinine levels had remained stable for more than 4 months after the procedure. Our study suggests that dialytic ultrafiltration of ascites by hemofilter is a safe method in the management of patients with refractory ascites and renal insufficiency.
UR - http://www.scopus.com/inward/record.url?scp=0023220270&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023220270&partnerID=8YFLogxK
M3 - Article
C2 - 3605027
AN - SCOPUS:0023220270
VL - 82
SP - 665
EP - 668
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
SN - 0002-9270
IS - 7
ER -