Diagnostic yield of cytologic analysis of pericardial effusion in dogs

L. A. Cagle, Steven E Epstein, Sean D Owens, M. S. Mellema, Katrina Hopper, A. G. Burton

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background: Pericardial effusion cytology is believed by many to be of limited value, yet few studies have evaluated its diagnostic utility. Objectives: To determine the diagnostic utility of cytologic analysis of pericardial effusion in dogs and to determine if consideration of additional data could improve the diagnostic yield. Animals: Two hundred and fifty-nine dogs with cytologic analysis of pericardial effusion performed between April 1990 and June 2012. Methods: Electronic medical records from a university teaching hospital were retrospectively reviewed; signalment, complete blood count, serum biochemistry, cytologic analysis of pericardial effusion, and echocardiographic data were recorded. Cytology was classified as diagnostic (infectious or neoplastic) or nondiagnostic (hemorrhagic or other) and groups were compared with multiple Student's t-tests. Results: Cytology was grouped as nondiagnostic (92.3%) or diagnostic (7.7%) and characterized as hemorrhagic (90%), neoplastic (4.6%), infectious (3.1%), or other (2.3%). Overall cytologic analysis of pericardial effusion diagnostic utility was 7.7% and increased to 20.3% if the effusion hematocrit (HCT) <10%; echocardiographic evidence of a mass did not result in a significant increase in the diagnostic utility. Conclusions and Clinical Importance: The diagnostic utility of cytologic analysis of canine pericardial effusion is variable depending on the underlying etiology. In this group of dogs, the diagnostic yield of cytologic analysis was greater for pericardial effusion samples in which the HCT was less than 10%.

Original languageEnglish (US)
Pages (from-to)66-71
Number of pages6
JournalJournal of Veterinary Internal Medicine
Volume28
Issue number1
DOIs
StatePublished - 2014

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pericardial effusion
Pericardial Effusion
Dogs
dogs
cell biology
Cell Biology
Hematocrit
hematocrit
Blood Cell Count
Electronic Health Records
blood serum
Teaching Hospitals
Biochemistry
biochemistry
electronics
etiology
Canidae
Students
blood
Serum

Keywords

  • Cardiac tamponade
  • Cytology
  • Hemangiosarcoma
  • Idiopathic
  • Mesothelioma

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Diagnostic yield of cytologic analysis of pericardial effusion in dogs. / Cagle, L. A.; Epstein, Steven E; Owens, Sean D; Mellema, M. S.; Hopper, Katrina; Burton, A. G.

In: Journal of Veterinary Internal Medicine, Vol. 28, No. 1, 2014, p. 66-71.

Research output: Contribution to journalArticle

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