Diagnosis of fish and shellfish allergies

Wai Sze Tong, Agatha W.T. Yuen, Christine Y.Y. Wai, Nicki Y.H. Leung, Ka Hou Chu, Patrick S Leung

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Seafood allergy is a hypersensitive disorder with increasing prevalence worldwide. Effective and accurate diagnostic workup for seafood allergy is essential for clinicians and patients. Parvalbumin and tropomyosin are the most common fish and shellfish allergens, respectively. The diagnosis of seafood allergies is complicated by cross-reactivity among fish allergens and between shellfish allergens and other arthropods. Current clinical diagnosis of seafood allergy is a complex algorithm that includes clinical assessment, skin prick test, specific IgE measurement, and oral food challenges. Emerging diagnostic strategies, such as component-resolved diagnosis (CRD), which uses single allergenic components for assessment of epitope specific IgE, can provide critical information in predicting individualized sensitization patterns and risk of severe allergic reactions. Further understanding of the molecular identities and characteristics of seafood allergens can advance the development of CRD and lead to more precise diagnosis and improved clinical management of seafood allergies.

Original languageEnglish (US)
Pages (from-to)247-260
Number of pages14
JournalJournal of Asthma and Allergy
Volume11
DOIs
StatePublished - Jan 1 2018

Fingerprint

Seafood
Hypersensitivity
Fishes
Allergens
Shellfish
Immunoglobulin E
Parvalbumins
Tropomyosin
Arthropods
Skin Tests
Shellfish Hypersensitivity
Epitopes
Food

Keywords

  • Component-resolved diagnosis
  • DBPCFC
  • ImmunoCAP
  • ISAC
  • Skin prick test

ASJC Scopus subject areas

  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

Cite this

Tong, W. S., Yuen, A. W. T., Wai, C. Y. Y., Leung, N. Y. H., Chu, K. H., & Leung, P. S. (2018). Diagnosis of fish and shellfish allergies. Journal of Asthma and Allergy, 11, 247-260. https://doi.org/10.2147/JAA.S142476

Diagnosis of fish and shellfish allergies. / Tong, Wai Sze; Yuen, Agatha W.T.; Wai, Christine Y.Y.; Leung, Nicki Y.H.; Chu, Ka Hou; Leung, Patrick S.

In: Journal of Asthma and Allergy, Vol. 11, 01.01.2018, p. 247-260.

Research output: Contribution to journalReview article

Tong, WS, Yuen, AWT, Wai, CYY, Leung, NYH, Chu, KH & Leung, PS 2018, 'Diagnosis of fish and shellfish allergies', Journal of Asthma and Allergy, vol. 11, pp. 247-260. https://doi.org/10.2147/JAA.S142476
Tong, Wai Sze ; Yuen, Agatha W.T. ; Wai, Christine Y.Y. ; Leung, Nicki Y.H. ; Chu, Ka Hou ; Leung, Patrick S. / Diagnosis of fish and shellfish allergies. In: Journal of Asthma and Allergy. 2018 ; Vol. 11. pp. 247-260.
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