Assays that use rhesus macaque whole blood and an antigen capture enzyme-linked immunosorbent assay for the simian immunodeficiency virus (SIV) p27 core protein were developed for the isolation of SIV from the blood of infected animals, the titration of infectivity of SIV inocula, and the quantitation of virus neutralizing antibodies in serum. These assays required small amounts of whole blood, were adaptable to a microtiter format, and used substrates mainly of rhesus macaque origin.
|Original language||English (US)|
|Number of pages||6|
|Journal||Journal of Clinical Microbiology|
|State||Published - 1991|
ASJC Scopus subject areas
- Microbiology (medical)