Development of larval schistosoma japonicum blocked in oncomelania hupensis by pre-infection with larval exorchis Sp.

Chong Ti Tang, Ming Ke Lu, Yue Guo, Yi Nan Wang, Jin Yong Peng, Wei Bao Wu, Wen Hong Li, Bart C Weimer, Dong Chen

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Schistosomiasis continues to be a significant public health threat in the world. In the area of parasitic diseases, it is widely considered second only to malaria as a global health problem, with an incalculable drain on the economic resources of countries where it is endemic. Schistosoma japonicum is widespread in eastern and southeastern Asia, where the amphibious snail, Oncomelania hupensis, is the intermediate host. In the present study, we found that infection of O. hupensis with the mature eggs of another trematode, Exorchis sp., inhibited development of S. japonicum mother sporocysts in O. hupensis. Exorchis sp. commonly infects the edible fish Parasilurus asotus in China, but it is harmless to humans. This discovery provides an opportunity for possible biological control of S. japonicum infection and transmission. Additionally, it has the potential to substantially reduce the impact of the global S. japonicum that is independent of antihelminthic use. The mechanisms used by Exorchis sp. to inhibit infection by S. japonicum in the snail require further investigation.

Original languageEnglish (US)
Pages (from-to)1321-1325
Number of pages5
JournalJournal of Parasitology
Volume95
Issue number6
DOIs
StatePublished - Dec 2009

Fingerprint

Oncomelania
Schistosoma japonicum
larval development
snail
Infection
infection
parasitic disease
schistosomiasis
Snails
sporocysts (Trematoda)
intermediate host
malaria
snails
biological control
drain
public health
economic resources
Southeastern Asia
Parasitic Diseases
Infectious Disease Transmission

ASJC Scopus subject areas

  • Parasitology
  • Ecology, Evolution, Behavior and Systematics
  • Medicine(all)

Cite this

Development of larval schistosoma japonicum blocked in oncomelania hupensis by pre-infection with larval exorchis Sp. / Tang, Chong Ti; Lu, Ming Ke; Guo, Yue; Wang, Yi Nan; Peng, Jin Yong; Wu, Wei Bao; Li, Wen Hong; Weimer, Bart C; Chen, Dong.

In: Journal of Parasitology, Vol. 95, No. 6, 12.2009, p. 1321-1325.

Research output: Contribution to journalArticle

Tang, Chong Ti ; Lu, Ming Ke ; Guo, Yue ; Wang, Yi Nan ; Peng, Jin Yong ; Wu, Wei Bao ; Li, Wen Hong ; Weimer, Bart C ; Chen, Dong. / Development of larval schistosoma japonicum blocked in oncomelania hupensis by pre-infection with larval exorchis Sp. In: Journal of Parasitology. 2009 ; Vol. 95, No. 6. pp. 1321-1325.
@article{5465e9a54478400988e23db42efc2dd9,
title = "Development of larval schistosoma japonicum blocked in oncomelania hupensis by pre-infection with larval exorchis Sp.",
abstract = "Schistosomiasis continues to be a significant public health threat in the world. In the area of parasitic diseases, it is widely considered second only to malaria as a global health problem, with an incalculable drain on the economic resources of countries where it is endemic. Schistosoma japonicum is widespread in eastern and southeastern Asia, where the amphibious snail, Oncomelania hupensis, is the intermediate host. In the present study, we found that infection of O. hupensis with the mature eggs of another trematode, Exorchis sp., inhibited development of S. japonicum mother sporocysts in O. hupensis. Exorchis sp. commonly infects the edible fish Parasilurus asotus in China, but it is harmless to humans. This discovery provides an opportunity for possible biological control of S. japonicum infection and transmission. Additionally, it has the potential to substantially reduce the impact of the global S. japonicum that is independent of antihelminthic use. The mechanisms used by Exorchis sp. to inhibit infection by S. japonicum in the snail require further investigation.",
author = "Tang, {Chong Ti} and Lu, {Ming Ke} and Yue Guo and Wang, {Yi Nan} and Peng, {Jin Yong} and Wu, {Wei Bao} and Li, {Wen Hong} and Weimer, {Bart C} and Dong Chen",
year = "2009",
month = "12",
doi = "10.1645/GE-2055.1",
language = "English (US)",
volume = "95",
pages = "1321--1325",
journal = "Journal of Parasitology",
issn = "0022-3395",
publisher = "American Society of Parasitologists",
number = "6",

}

TY - JOUR

T1 - Development of larval schistosoma japonicum blocked in oncomelania hupensis by pre-infection with larval exorchis Sp.

AU - Tang, Chong Ti

AU - Lu, Ming Ke

AU - Guo, Yue

AU - Wang, Yi Nan

AU - Peng, Jin Yong

AU - Wu, Wei Bao

AU - Li, Wen Hong

AU - Weimer, Bart C

AU - Chen, Dong

PY - 2009/12

Y1 - 2009/12

N2 - Schistosomiasis continues to be a significant public health threat in the world. In the area of parasitic diseases, it is widely considered second only to malaria as a global health problem, with an incalculable drain on the economic resources of countries where it is endemic. Schistosoma japonicum is widespread in eastern and southeastern Asia, where the amphibious snail, Oncomelania hupensis, is the intermediate host. In the present study, we found that infection of O. hupensis with the mature eggs of another trematode, Exorchis sp., inhibited development of S. japonicum mother sporocysts in O. hupensis. Exorchis sp. commonly infects the edible fish Parasilurus asotus in China, but it is harmless to humans. This discovery provides an opportunity for possible biological control of S. japonicum infection and transmission. Additionally, it has the potential to substantially reduce the impact of the global S. japonicum that is independent of antihelminthic use. The mechanisms used by Exorchis sp. to inhibit infection by S. japonicum in the snail require further investigation.

AB - Schistosomiasis continues to be a significant public health threat in the world. In the area of parasitic diseases, it is widely considered second only to malaria as a global health problem, with an incalculable drain on the economic resources of countries where it is endemic. Schistosoma japonicum is widespread in eastern and southeastern Asia, where the amphibious snail, Oncomelania hupensis, is the intermediate host. In the present study, we found that infection of O. hupensis with the mature eggs of another trematode, Exorchis sp., inhibited development of S. japonicum mother sporocysts in O. hupensis. Exorchis sp. commonly infects the edible fish Parasilurus asotus in China, but it is harmless to humans. This discovery provides an opportunity for possible biological control of S. japonicum infection and transmission. Additionally, it has the potential to substantially reduce the impact of the global S. japonicum that is independent of antihelminthic use. The mechanisms used by Exorchis sp. to inhibit infection by S. japonicum in the snail require further investigation.

UR - http://www.scopus.com/inward/record.url?scp=76749139871&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=76749139871&partnerID=8YFLogxK

U2 - 10.1645/GE-2055.1

DO - 10.1645/GE-2055.1

M3 - Article

C2 - 19663532

AN - SCOPUS:76749139871

VL - 95

SP - 1321

EP - 1325

JO - Journal of Parasitology

JF - Journal of Parasitology

SN - 0022-3395

IS - 6

ER -