Development and validation of a photonumeric scale for evaluation of transverse neck lines

Derek Jones, Alastair Carruthers, Bhushan Hardas, Diane K. Murphy, Jonathan M Sykes, Lisa Donofrio, Jean Carruthers, Lela Creutz, Ann Marx, Sara Dill

Research output: Contribution to journalArticle

3 Scopus citations


Background: A validated scale is needed for objective and reproducible comparisons of horizontal neck lines before and after treatment in practice and clinical studies. Objective: To describe the development and validation of the 5-point photonumeric Allergan Transverse Neck Lines Scale. Methods: The Allergan Transverse Neck Lines Scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each scale grade. The clinical significance of a 1-point score difference was evaluated in a review of multiple image pairs representing varying differences in severity. Interrater and intrarater reliability was evaluated in a live-subject rating validation study (N = 297) completed during 2 sessions occurring 3 weeks apart. Results: A difference of ≥1 point on the scale was shown to reflect a clinically significant difference (mean [95% confidence interval] absolute score difference, 1.22 [1.09-1.35] for clinically different image pairs and 0.57 [0.42-0.72] for not clinically different pairs). Intrarater agreement between the 2 live-subject rating validation sessions was substantial (mean weighted kappa = 0.78). Interrater agreement was substantial during the second rating session (0.73, primary end point). Conclusion: The Allergan Transverse Neck Lines Scale is a validated and reliable scale for rating of severity of neck lines.

Original languageEnglish (US)
Pages (from-to)S235-S242
JournalDermatologic Surgery
StatePublished - 2016


ASJC Scopus subject areas

  • Surgery
  • Dermatology

Cite this

Jones, D., Carruthers, A., Hardas, B., Murphy, D. K., Sykes, J. M., Donofrio, L., Carruthers, J., Creutz, L., Marx, A., & Dill, S. (2016). Development and validation of a photonumeric scale for evaluation of transverse neck lines. Dermatologic Surgery, 42, S235-S242.