Development and characterization of a monoclonal antibody to class II MHC antigens in rhesus macaques

Peter F Moore, L. R. Ellingsworth, G. P. Toedter

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

The characterization of a monoclonal antibody with specificity for a monomorphic determinant on rhesus macaque class II antigens is described. This antibody, designated 2D16, is an IgG2b immunoglobulin which also displayed useful cross‐reactivity with lymphoreticular cells and cell lines of other species including man, bonnet and stumptail macaques, sheep, dog and horse. Limited polymorphism of the 2D16 epitope was observed in the dog.

Original languageEnglish (US)
Pages (from-to)88-99
Number of pages12
JournalTissue Antigens
Volume28
Issue number2
DOIs
StatePublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Genetics

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