Developing guidelines for biotechnology drug use: Experience with antithrombin III

D. R. Romac, P. Poole, John T Owings, K. Mahackian, G. Foulke, R. S. Tharratt, Timothy E Albertson

Research output: Contribution to journalArticlepeer-review


Development of institutional guidelines for use of high-cost biotechnology drugs, such as antithrombin III, is a valuable tool in formulary management. This article describes the process by which the University of California Davis Medical Center used an ad hoc committee to the P and T Committee to develop guidelines for antithrombin III use. Performing an objective analysis of available literature to address the appropriate role of a biotechnology agent is necessary to develop consensus guidelines. Approval of use guidelines by the P and T Committee provides the necessary structure for optimal use of biotechnology agents, such as antithrombin III.

Original languageEnglish (US)
Pages (from-to)520-531
Number of pages12
Issue number9
StatePublished - 1995

ASJC Scopus subject areas

  • Pharmaceutical Science


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