Determinination of plasma osmolality and agreement between measured and calculated values in healthy adult Hispaniolan Amazon parrots (Amazona ventralis)

Mark J. Acierno, Mark A. Mitchell, Diana M. Freeman, Patricia J. Schuster, David Guzman, Thomas N. Tully

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objective - To determine plasma osmolality in healthy adult Hispaniolan Amazon parrots (Amazona ventralis) and validate osmolality equations in these parrots. Animals - 20 healthy adult Hispaniolan Amazon parrots. Procedures - A blood sample (0.5 mL) was collected from the right jugular vein of each parrot and placed into a lithium heparin microtainer tube. Samples were centrifuged, and plasma was harvested and frozen at -30°C. Samples were thawed, and plasma osmolality was measured in duplicate with a freezing-point depression osmometer. The mean value was calculated for the 2 osmolality measurements. Results - Plasma osmolality values were normally distributed, with a mean ± SD of 326.0 ± 6.878 mOsm/kg.The equations (2 X [Na+ + K+]) + (glucose/18), which resulted in bias of 2.3333 mOsm/kg and limits of agreement of -7.0940 to 11.7606 mOsm/kg, and (2 X [Na+ + K+]) + (uric acid concentration/16.8) + (glucose concentration/18), which resulted in bias of 5.8117 mOsm/kg and limits of agreement of -14.6640 to 3.0406 mOsm/kg, yielded calculated values that were in good agreement with the measured osmolality. Conclusions and Clinical Relevance - IV administration of large amounts of hypotonic fluids can have catastrophic'consequences. Osmolality of the plasma from parrots in this study was significantly higher than that of commercially available prepackaged fluids. Therefore, such fluids should be used with caution in Hispaniolan Amazon parrots as well as other psittacines. Additional studies are needed to determine whether the estimation of osmolality has the same clinical value in psittacines as it does in other animals.

Original languageEnglish (US)
Pages (from-to)1151-1154
Number of pages4
JournalAmerican Journal of Veterinary Research
Volume70
Issue number9
DOIs
StatePublished - Sep 1 2009
Externally publishedYes

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Amazona
parrots
osmolality
Osmolar Concentration
Parrots
Psittaciformes
Glucose
glucose
lithium
Jugular Veins
jugular vein
freezing point
heparin
uric acid
Uric Acid
Lithium
intravenous injection
sampling
Freezing
Heparin

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Determinination of plasma osmolality and agreement between measured and calculated values in healthy adult Hispaniolan Amazon parrots (Amazona ventralis). / Acierno, Mark J.; Mitchell, Mark A.; Freeman, Diana M.; Schuster, Patricia J.; Guzman, David; Tully, Thomas N.

In: American Journal of Veterinary Research, Vol. 70, No. 9, 01.09.2009, p. 1151-1154.

Research output: Contribution to journalArticle

Acierno, Mark J. ; Mitchell, Mark A. ; Freeman, Diana M. ; Schuster, Patricia J. ; Guzman, David ; Tully, Thomas N. / Determinination of plasma osmolality and agreement between measured and calculated values in healthy adult Hispaniolan Amazon parrots (Amazona ventralis). In: American Journal of Veterinary Research. 2009 ; Vol. 70, No. 9. pp. 1151-1154.
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abstract = "Objective - To determine plasma osmolality in healthy adult Hispaniolan Amazon parrots (Amazona ventralis) and validate osmolality equations in these parrots. Animals - 20 healthy adult Hispaniolan Amazon parrots. Procedures - A blood sample (0.5 mL) was collected from the right jugular vein of each parrot and placed into a lithium heparin microtainer tube. Samples were centrifuged, and plasma was harvested and frozen at -30°C. Samples were thawed, and plasma osmolality was measured in duplicate with a freezing-point depression osmometer. The mean value was calculated for the 2 osmolality measurements. Results - Plasma osmolality values were normally distributed, with a mean ± SD of 326.0 ± 6.878 mOsm/kg.The equations (2 X [Na+ + K+]) + (glucose/18), which resulted in bias of 2.3333 mOsm/kg and limits of agreement of -7.0940 to 11.7606 mOsm/kg, and (2 X [Na+ + K+]) + (uric acid concentration/16.8) + (glucose concentration/18), which resulted in bias of 5.8117 mOsm/kg and limits of agreement of -14.6640 to 3.0406 mOsm/kg, yielded calculated values that were in good agreement with the measured osmolality. Conclusions and Clinical Relevance - IV administration of large amounts of hypotonic fluids can have catastrophic'consequences. Osmolality of the plasma from parrots in this study was significantly higher than that of commercially available prepackaged fluids. Therefore, such fluids should be used with caution in Hispaniolan Amazon parrots as well as other psittacines. Additional studies are needed to determine whether the estimation of osmolality has the same clinical value in psittacines as it does in other animals.",
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AU - Acierno, Mark J.

AU - Mitchell, Mark A.

AU - Freeman, Diana M.

AU - Schuster, Patricia J.

AU - Guzman, David

AU - Tully, Thomas N.

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N2 - Objective - To determine plasma osmolality in healthy adult Hispaniolan Amazon parrots (Amazona ventralis) and validate osmolality equations in these parrots. Animals - 20 healthy adult Hispaniolan Amazon parrots. Procedures - A blood sample (0.5 mL) was collected from the right jugular vein of each parrot and placed into a lithium heparin microtainer tube. Samples were centrifuged, and plasma was harvested and frozen at -30°C. Samples were thawed, and plasma osmolality was measured in duplicate with a freezing-point depression osmometer. The mean value was calculated for the 2 osmolality measurements. Results - Plasma osmolality values were normally distributed, with a mean ± SD of 326.0 ± 6.878 mOsm/kg.The equations (2 X [Na+ + K+]) + (glucose/18), which resulted in bias of 2.3333 mOsm/kg and limits of agreement of -7.0940 to 11.7606 mOsm/kg, and (2 X [Na+ + K+]) + (uric acid concentration/16.8) + (glucose concentration/18), which resulted in bias of 5.8117 mOsm/kg and limits of agreement of -14.6640 to 3.0406 mOsm/kg, yielded calculated values that were in good agreement with the measured osmolality. Conclusions and Clinical Relevance - IV administration of large amounts of hypotonic fluids can have catastrophic'consequences. Osmolality of the plasma from parrots in this study was significantly higher than that of commercially available prepackaged fluids. Therefore, such fluids should be used with caution in Hispaniolan Amazon parrots as well as other psittacines. Additional studies are needed to determine whether the estimation of osmolality has the same clinical value in psittacines as it does in other animals.

AB - Objective - To determine plasma osmolality in healthy adult Hispaniolan Amazon parrots (Amazona ventralis) and validate osmolality equations in these parrots. Animals - 20 healthy adult Hispaniolan Amazon parrots. Procedures - A blood sample (0.5 mL) was collected from the right jugular vein of each parrot and placed into a lithium heparin microtainer tube. Samples were centrifuged, and plasma was harvested and frozen at -30°C. Samples were thawed, and plasma osmolality was measured in duplicate with a freezing-point depression osmometer. The mean value was calculated for the 2 osmolality measurements. Results - Plasma osmolality values were normally distributed, with a mean ± SD of 326.0 ± 6.878 mOsm/kg.The equations (2 X [Na+ + K+]) + (glucose/18), which resulted in bias of 2.3333 mOsm/kg and limits of agreement of -7.0940 to 11.7606 mOsm/kg, and (2 X [Na+ + K+]) + (uric acid concentration/16.8) + (glucose concentration/18), which resulted in bias of 5.8117 mOsm/kg and limits of agreement of -14.6640 to 3.0406 mOsm/kg, yielded calculated values that were in good agreement with the measured osmolality. Conclusions and Clinical Relevance - IV administration of large amounts of hypotonic fluids can have catastrophic'consequences. Osmolality of the plasma from parrots in this study was significantly higher than that of commercially available prepackaged fluids. Therefore, such fluids should be used with caution in Hispaniolan Amazon parrots as well as other psittacines. Additional studies are needed to determine whether the estimation of osmolality has the same clinical value in psittacines as it does in other animals.

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