TY - JOUR
T1 - Determination of serologic and colostral response in late-gestation cows vaccinated with a Mycoplasma bovis bacterin
AU - Calloway, Christopher D.
AU - Schultz, Loren G.
AU - Chigerwe, Munashe
AU - Larson, Robert L.
AU - Youngquist, Robert S.
AU - Steevens, Barry J.
PY - 2008/7
Y1 - 2008/7
N2 - Objective - To determine whether vaccinating cows during late gestation against Mycoplasma bovis will result in adequate concentrations of M bovis-specific lgG1 in serum, colostrum, and milk. Animals - 78 dairy cows. Procedures - Serum samples were obtained 60 and 39 days prior to expected parturition in vaccinated and control cows from a single herd. Serum and colostrum samples were also obtained at parturition. Milk samples were obtained 7 to 14 days after parturition. Samples were analyzed for anti-M bovis lgG1 concentrations. Results - Prior to vaccination, control and vaccinated cows had similar anti-M bovis lgG1 concentrations. After initial vaccination and subsequent booster and at parturition, there was a significant difference between the 2 groups, with vaccinated cows having higher lgG concentrations. Colostrum from vaccinated cows had higher anti-M bovis lgG1 concentrations, compared with control cows; however, lgG1 concentrations in milk did not differ between the 2 groups. Conclusions and Clinical Relevance - Vaccination of late-gestation cows resulted in increased concentrations of anti-M bovis lgG1 in colostrum. However ingestion of colostrum by calves may not guarantee protection against M bovis infection.
AB - Objective - To determine whether vaccinating cows during late gestation against Mycoplasma bovis will result in adequate concentrations of M bovis-specific lgG1 in serum, colostrum, and milk. Animals - 78 dairy cows. Procedures - Serum samples were obtained 60 and 39 days prior to expected parturition in vaccinated and control cows from a single herd. Serum and colostrum samples were also obtained at parturition. Milk samples were obtained 7 to 14 days after parturition. Samples were analyzed for anti-M bovis lgG1 concentrations. Results - Prior to vaccination, control and vaccinated cows had similar anti-M bovis lgG1 concentrations. After initial vaccination and subsequent booster and at parturition, there was a significant difference between the 2 groups, with vaccinated cows having higher lgG concentrations. Colostrum from vaccinated cows had higher anti-M bovis lgG1 concentrations, compared with control cows; however, lgG1 concentrations in milk did not differ between the 2 groups. Conclusions and Clinical Relevance - Vaccination of late-gestation cows resulted in increased concentrations of anti-M bovis lgG1 in colostrum. However ingestion of colostrum by calves may not guarantee protection against M bovis infection.
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U2 - 10.2460/ajvr.69.7.912
DO - 10.2460/ajvr.69.7.912
M3 - Article
C2 - 18593245
AN - SCOPUS:48049094976
VL - 69
SP - 912
EP - 915
JO - American Journal of Veterinary Research
JF - American Journal of Veterinary Research
SN - 0002-9645
IS - 7
ER -