Abstract
The ability to detect dementia of the Alzheimer type (DAT) in a community-dwelling sample of elderly individuals on the basis of neuropsychological test performance was examined. Three hundred sixty community-dwelling individuals were identified by neurological examination as having probable or possible Alzheimer's disease, being at risk for Alzheimer's disease, or having no cognitive impairment. A logistic model comprised of tests of verbal and nonverbal memory, mental flexibility, and confrontation naming correctly classified 82% of DAT subjects and 98% of normal elderly subjects. The logistic model classified 77% of subjects who were diagnosed as at risk for Alzheimer's disease as being cognitively normal. A cross-validation with a clinically based sample of subjects correctly classified 89% of DAT patients and 100% of normal control subjects. The results suggest that psychometric discrimination of dementia may be less accurate in community-dwelling populations than in clinically based samples. (JINS, 1995, 1, 252-260.).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 252-260 |
| Number of pages | 9 |
| Journal | Journal of the International Neuropsychological Society |
| Volume | 1 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jan 1 1995 |
| Externally published | Yes |
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Keywords
- Alzheimer's disease
- Dementia
- Neuropsychological testing
ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Psychology
- Clinical Neurology
- Psychiatry and Mental health
Cite this
Detection of dementia of the Alzheimer type in a population-based sample : Neuropsychological test performance. / Cahn-Weiner, Deborah; Butters, Nelson; Cahn, Deborah A.; Salmon, David P.; Wiederholt, Wigbert C.; Corey-Bloom, Jody; Edelstein, Sharon L.; Barrett-Connor, Elizabeth.
In: Journal of the International Neuropsychological Society, Vol. 1, No. 3, 01.01.1995, p. 252-260.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Detection of dementia of the Alzheimer type in a population-based sample
T2 - Neuropsychological test performance
AU - Cahn-Weiner, Deborah
AU - Butters, Nelson
AU - Cahn, Deborah A.
AU - Salmon, David P.
AU - Wiederholt, Wigbert C.
AU - Corey-Bloom, Jody
AU - Edelstein, Sharon L.
AU - Barrett-Connor, Elizabeth
PY - 1995/1/1
Y1 - 1995/1/1
N2 - The ability to detect dementia of the Alzheimer type (DAT) in a community-dwelling sample of elderly individuals on the basis of neuropsychological test performance was examined. Three hundred sixty community-dwelling individuals were identified by neurological examination as having probable or possible Alzheimer's disease, being at risk for Alzheimer's disease, or having no cognitive impairment. A logistic model comprised of tests of verbal and nonverbal memory, mental flexibility, and confrontation naming correctly classified 82% of DAT subjects and 98% of normal elderly subjects. The logistic model classified 77% of subjects who were diagnosed as at risk for Alzheimer's disease as being cognitively normal. A cross-validation with a clinically based sample of subjects correctly classified 89% of DAT patients and 100% of normal control subjects. The results suggest that psychometric discrimination of dementia may be less accurate in community-dwelling populations than in clinically based samples. (JINS, 1995, 1, 252-260.).
AB - The ability to detect dementia of the Alzheimer type (DAT) in a community-dwelling sample of elderly individuals on the basis of neuropsychological test performance was examined. Three hundred sixty community-dwelling individuals were identified by neurological examination as having probable or possible Alzheimer's disease, being at risk for Alzheimer's disease, or having no cognitive impairment. A logistic model comprised of tests of verbal and nonverbal memory, mental flexibility, and confrontation naming correctly classified 82% of DAT subjects and 98% of normal elderly subjects. The logistic model classified 77% of subjects who were diagnosed as at risk for Alzheimer's disease as being cognitively normal. A cross-validation with a clinically based sample of subjects correctly classified 89% of DAT patients and 100% of normal control subjects. The results suggest that psychometric discrimination of dementia may be less accurate in community-dwelling populations than in clinically based samples. (JINS, 1995, 1, 252-260.).
KW - Alzheimer's disease
KW - Dementia
KW - Neuropsychological testing
UR - http://www.scopus.com/inward/record.url?scp=0029295098&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029295098&partnerID=8YFLogxK
U2 - 10.1017/S1355617700000242
DO - 10.1017/S1355617700000242
M3 - Article
C2 - 9375219
AN - SCOPUS:0029295098
VL - 1
SP - 252
EP - 260
JO - Journal of the International Neuropsychological Society
JF - Journal of the International Neuropsychological Society
SN - 1355-6177
IS - 3
ER -