Detection of Bartonella infection in pet dogs from Manila, the Philippines

Gar A. Singer, Felina P. Loya, Wallis D. Lapsley, Bret Z. Tobar, Sixto Carlos, Rhodora S. Carlos, Enrique T. Carlos, Davin Edric V. Adao, Windell L. Rivera, David A. Jaffe, Jonna A.K. Mazet, Bruno B. Chomel

Research output: Contribution to journalArticle

Abstract

Dogs can be infected by a wide range of Bartonella spp., but studies regarding the prevalence of Bartonella infection in dogs in the Philippines have not been conducted. This study aimed at determining the prevalence of Bartonella infection in pets dogs from two veterinary clinics in Metro Manila, The Philippines, using both serology and polymerase chain reaction (PCR). Blood samples from 116 dogs from two different groups, one of 60 mainly “healthy dogs” and the other one of 56 dogs enrolled in a tick-borne disease suspect group, were tested for presence of B. henselae antibodies and to detect Bartonella DNA using primers specific for the citrate synthase gene. Seroprevalence for B. henselae was very low (2.6%), as the only three (5%) seropositive dogs (titer 1:64) where among the healthy pet dog group. Following subsequent sequencing, 13 samples, all from the tick-borne disease group, were determined positive for B. henselae (11.2%). This is the first study to report dog infection with B. henselae in the Philippines.

Original languageEnglish (US)
Article number105277
JournalActa Tropica
Volume205
DOIs
StatePublished - May 2020

Keywords

  • Bartonella henselae
  • Dogs
  • Dogs Philippines
  • PCR
  • Serology

ASJC Scopus subject areas

  • Parasitology
  • veterinary (miscalleneous)
  • Insect Science
  • Infectious Diseases

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  • Cite this

    Singer, G. A., Loya, F. P., Lapsley, W. D., Tobar, B. Z., Carlos, S., Carlos, R. S., Carlos, E. T., Adao, D. E. V., Rivera, W. L., Jaffe, D. A., Mazet, J. A. K., & Chomel, B. B. (2020). Detection of Bartonella infection in pet dogs from Manila, the Philippines. Acta Tropica, 205, [105277]. https://doi.org/10.1016/j.actatropica.2019.105277