TY - JOUR
T1 - Detecting Candida albicans in human milk
AU - Morrill, Jimi Francis
AU - Pappagianis, Demosthenes
AU - Heinig, M. Jane
AU - Lönnerdal, Bo
AU - Dewey, Kathryn G.
PY - 2003/1/1
Y1 - 2003/1/1
N2 - Procedures for diagnosis of mammary candidosis, including laboratory confirmation, are not well defined. Lactoferrin present in human milk can inhibit growth of Candida albicans, thereby limiting the ability to detect yeast infections. The inhibitory effect of various lactoferrin concentrations on the growth of C. albicans in whole human milk was studied. The addition of iron to the milk led to a two- to three-fold increase in cell counts when milk contained 3.0 mg of lactoferrin/ml and markedly reduced the likelihood of false-negative culture results. This method may provide the necessary objective support needed for diagnosis of mammary candidosis.
AB - Procedures for diagnosis of mammary candidosis, including laboratory confirmation, are not well defined. Lactoferrin present in human milk can inhibit growth of Candida albicans, thereby limiting the ability to detect yeast infections. The inhibitory effect of various lactoferrin concentrations on the growth of C. albicans in whole human milk was studied. The addition of iron to the milk led to a two- to three-fold increase in cell counts when milk contained 3.0 mg of lactoferrin/ml and markedly reduced the likelihood of false-negative culture results. This method may provide the necessary objective support needed for diagnosis of mammary candidosis.
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U2 - 10.1128/JCM.41.1.475-478.2003
DO - 10.1128/JCM.41.1.475-478.2003
M3 - Article
C2 - 12517899
AN - SCOPUS:0037232280
VL - 41
SP - 475
EP - 478
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
SN - 0095-1137
IS - 1
ER -