Detecting Candida albicans in human milk

Jimi Francis Morrill, Demosthenes Pappagianis, M. Jane Heinig, Bo Lönnerdal, Kathryn G. Dewey

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Procedures for diagnosis of mammary candidosis, including laboratory confirmation, are not well defined. Lactoferrin present in human milk can inhibit growth of Candida albicans, thereby limiting the ability to detect yeast infections. The inhibitory effect of various lactoferrin concentrations on the growth of C. albicans in whole human milk was studied. The addition of iron to the milk led to a two- to three-fold increase in cell counts when milk contained 3.0 mg of lactoferrin/ml and markedly reduced the likelihood of false-negative culture results. This method may provide the necessary objective support needed for diagnosis of mammary candidosis.

Original languageEnglish (US)
Pages (from-to)475-478
Number of pages4
JournalJournal of Clinical Microbiology
Volume41
Issue number1
DOIs
StatePublished - Jan 1 2003

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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    Morrill, J. F., Pappagianis, D., Heinig, M. J., Lönnerdal, B., & Dewey, K. G. (2003). Detecting Candida albicans in human milk. Journal of Clinical Microbiology, 41(1), 475-478. https://doi.org/10.1128/JCM.41.1.475-478.2003