Design and development of an MR-compatible PET scanner for imaging small animals

J. E. Mackewn; D. Strul; W. A. Hallett; P. Halsted; R. A. Page; S. F. Keevil; S. C R Williams; Simon R Cherry; P. K. Marsden

Design and development of an MR-compatible PET scanner for imaging small animals

J. E. Mackewn, D. Strul, W. A. Hallett, P. Halsted, R. A. Page, S. F. Keevil, S. C R Williams, Simon R Cherry, P. K. Marsden

Radiology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

An MR compatible PET system has been assigned and is currently under construction. It will consist of four concentric rings of LSO crystals, each coupled to one of eight multi-channel photomultplier tubes via 3.5m optical fibres. The photomultiplier tubes may be located outside the main magnetic field of the MR scanner. A highly reproducible method has been established to optimise the amount of scintillation light that reaches the PM tubes, as this factor will heavily influence the scanner performance. Two small sections of the scanner, each containing 4 by 4 crystal arrays, demonstrated good flood position histograms with all sixteen channels clearly identifiable. The light loss through a fibre of length of 3.25m was approximately 70%. The spatial resolution of the two arrays in coincidence was measured at 1.6mm (FWHM). The temporal resolution of one array in coincidence with a single LSO crystal was measured to be 10.9ns. A technique for improving sampling at the centre of the field of view within the scanner has also been investigated, whereby the concentric rings are offset with respect to one another. An offset of one quarter of the crystal width between layers results in significantly improved sampling. These results indicate that the scanner will be capable of carrying out the studies for which it has been designed.

Original language	English (US)
Title of host publication	IEEE Nuclear Science Symposium Conference Record
Editors	J.A. Seibert
Pages	3271-3274
Number of pages	4
Volume	5
State	Published - 2004
Event	2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors - Rome, Italy Duration: Oct 16 2004 → Oct 22 2004

Other

Other	2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors
Country	Italy
City	Rome
Period	10/16/04 → 10/22/04

ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Industrial and Manufacturing Engineering

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Design and development of an MR-compatible PET scanner for imaging small animals. / Mackewn, J. E.; Strul, D.; Hallett, W. A.; Halsted, P.; Page, R. A.; Keevil, S. F.; Williams, S. C R; Cherry, Simon R; Marsden, P. K.

IEEE Nuclear Science Symposium Conference Record. ed. / J.A. Seibert. Vol. 5 2004. p. 3271-3274 M6-1.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Mackewn, JE, Strul, D, Hallett, WA, Halsted, P, Page, RA, Keevil, SF, Williams, SCR, Cherry, SR & Marsden, PK 2004, Design and development of an MR-compatible PET scanner for imaging small animals. in JA Seibert (ed.), IEEE Nuclear Science Symposium Conference Record. vol. 5, M6-1, pp. 3271-3274, 2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors, Rome, Italy, 10/16/04.

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abstract = "An MR compatible PET system has been assigned and is currently under construction. It will consist of four concentric rings of LSO crystals, each coupled to one of eight multi-channel photomultplier tubes via 3.5m optical fibres. The photomultiplier tubes may be located outside the main magnetic field of the MR scanner. A highly reproducible method has been established to optimise the amount of scintillation light that reaches the PM tubes, as this factor will heavily influence the scanner performance. Two small sections of the scanner, each containing 4 by 4 crystal arrays, demonstrated good flood position histograms with all sixteen channels clearly identifiable. The light loss through a fibre of length of 3.25m was approximately 70%. The spatial resolution of the two arrays in coincidence was measured at 1.6mm (FWHM). The temporal resolution of one array in coincidence with a single LSO crystal was measured to be 10.9ns. A technique for improving sampling at the centre of the field of view within the scanner has also been investigated, whereby the concentric rings are offset with respect to one another. An offset of one quarter of the crystal width between layers results in significantly improved sampling. These results indicate that the scanner will be capable of carrying out the studies for which it has been designed.",

author = "Mackewn, {J. E.} and D. Strul and Hallett, {W. A.} and P. Halsted and Page, {R. A.} and Keevil, {S. F.} and Williams, {S. C R} and Cherry, {Simon R} and Marsden, {P. K.}",

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AU - Keevil, S. F.

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AB - An MR compatible PET system has been assigned and is currently under construction. It will consist of four concentric rings of LSO crystals, each coupled to one of eight multi-channel photomultplier tubes via 3.5m optical fibres. The photomultiplier tubes may be located outside the main magnetic field of the MR scanner. A highly reproducible method has been established to optimise the amount of scintillation light that reaches the PM tubes, as this factor will heavily influence the scanner performance. Two small sections of the scanner, each containing 4 by 4 crystal arrays, demonstrated good flood position histograms with all sixteen channels clearly identifiable. The light loss through a fibre of length of 3.25m was approximately 70%. The spatial resolution of the two arrays in coincidence was measured at 1.6mm (FWHM). The temporal resolution of one array in coincidence with a single LSO crystal was measured to be 10.9ns. A technique for improving sampling at the centre of the field of view within the scanner has also been investigated, whereby the concentric rings are offset with respect to one another. An offset of one quarter of the crystal width between layers results in significantly improved sampling. These results indicate that the scanner will be capable of carrying out the studies for which it has been designed.

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Design and development of an MR-compatible PET scanner for imaging small animals

Abstract

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ASJC Scopus subject areas

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