Abstract
Portable and wearable medical instruments are poised to play an increasingly important role in health monitoring. Mobile spirometers are available commercially, and are used to monitor patients with advanced lung disease. However, these commercial monitors have a fixed product architecture determined by the manufacturer, and researchers cannot easily experiment with new configurations or add additional novel sensors over time. Spirometry combined with exhaled breath metabolite monitoring has the potential to transform healthcare and improve clinical management strategies. This research provides an updated design and benchmark testing for a flexible, portable, open access architecture to measure lung function, using common Arduino/Android microcontroller technologies. To demonstrate the feasibility and the proof-of-concept of this easily-adaptable platform technology, we had 43 subjects (healthy, and those with lung diseases) perform three spirometry maneuvers using our reconfigurable device and an office-based commercial spirometer. We found that our system compared favorably with the traditional spirometer, with high accuracy and agreement for forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC), and gas measurements were feasible. This provides an adaptable/reconfigurable open access “personalized medicine” platform for researchers and patients, and new chemical sensors and other modular instrumentation can extend the flexibility of the device in the future.
| Original language | English (US) |
|---|---|
| Article number | 100 |
| Journal | Diagnostics |
| Volume | 9 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 1 2019 |
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Keywords
- Breath analysis
- Personalized medicine
- Spirometry
- Telehealth
ASJC Scopus subject areas
- Clinical Biochemistry
Cite this
Design and benchmark testing for open architecture reconfigurable mobile spirometer and exhaled breath monitor with GPS and data telemetry. / Fung, Alexander G.; Tan, Laren D.; Duong, Theresa N.; Schivo, Michael; Littlefield, Leslie; Delplanque, Jean Pierre; Davis, Cristina E.; Kenyon, Nicholas J.
In: Diagnostics, Vol. 9, No. 3, 100, 01.09.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Design and benchmark testing for open architecture reconfigurable mobile spirometer and exhaled breath monitor with GPS and data telemetry
AU - Fung, Alexander G.
AU - Tan, Laren D.
AU - Duong, Theresa N.
AU - Schivo, Michael
AU - Littlefield, Leslie
AU - Delplanque, Jean Pierre
AU - Davis, Cristina E.
AU - Kenyon, Nicholas J.
PY - 2019/9/1
Y1 - 2019/9/1
N2 - Portable and wearable medical instruments are poised to play an increasingly important role in health monitoring. Mobile spirometers are available commercially, and are used to monitor patients with advanced lung disease. However, these commercial monitors have a fixed product architecture determined by the manufacturer, and researchers cannot easily experiment with new configurations or add additional novel sensors over time. Spirometry combined with exhaled breath metabolite monitoring has the potential to transform healthcare and improve clinical management strategies. This research provides an updated design and benchmark testing for a flexible, portable, open access architecture to measure lung function, using common Arduino/Android microcontroller technologies. To demonstrate the feasibility and the proof-of-concept of this easily-adaptable platform technology, we had 43 subjects (healthy, and those with lung diseases) perform three spirometry maneuvers using our reconfigurable device and an office-based commercial spirometer. We found that our system compared favorably with the traditional spirometer, with high accuracy and agreement for forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC), and gas measurements were feasible. This provides an adaptable/reconfigurable open access “personalized medicine” platform for researchers and patients, and new chemical sensors and other modular instrumentation can extend the flexibility of the device in the future.
AB - Portable and wearable medical instruments are poised to play an increasingly important role in health monitoring. Mobile spirometers are available commercially, and are used to monitor patients with advanced lung disease. However, these commercial monitors have a fixed product architecture determined by the manufacturer, and researchers cannot easily experiment with new configurations or add additional novel sensors over time. Spirometry combined with exhaled breath metabolite monitoring has the potential to transform healthcare and improve clinical management strategies. This research provides an updated design and benchmark testing for a flexible, portable, open access architecture to measure lung function, using common Arduino/Android microcontroller technologies. To demonstrate the feasibility and the proof-of-concept of this easily-adaptable platform technology, we had 43 subjects (healthy, and those with lung diseases) perform three spirometry maneuvers using our reconfigurable device and an office-based commercial spirometer. We found that our system compared favorably with the traditional spirometer, with high accuracy and agreement for forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC), and gas measurements were feasible. This provides an adaptable/reconfigurable open access “personalized medicine” platform for researchers and patients, and new chemical sensors and other modular instrumentation can extend the flexibility of the device in the future.
KW - Breath analysis
KW - Personalized medicine
KW - Spirometry
KW - Telehealth
UR - http://www.scopus.com/inward/record.url?scp=85072610353&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85072610353&partnerID=8YFLogxK
U2 - 10.3390/diagnostics9030100
DO - 10.3390/diagnostics9030100
M3 - Article
AN - SCOPUS:85072610353
VL - 9
JO - Diagnostics
JF - Diagnostics
SN - 2075-4418
IS - 3
M1 - 100
ER -