Dermatologic manifestations of cytotoxic therapy

Victor Huang, Milan Anadkat

Research output: Contribution to journalReview article

13 Scopus citations

Abstract

Cytotoxic agents represent the oldest class of chemotherapy drugs. These agents interrupt the replication of rapidly dividing malignant and nonmalignant cells by interfering with DNA replication. Resultant toxicity commonly affects the bone marrow, skin, and intestinal epithelium. In addition, there exist specific dermatologic reaction patterns that may appear. The present review highlights the most common specific and nonspecific dermatologic adverse effects seen with cytotoxic chemotherapeutic agents.

Original languageEnglish (US)
Pages (from-to)401-410
Number of pages10
JournalDermatologic Therapy
Volume24
Issue number4
DOIs
StatePublished - Jul 1 2011
Externally publishedYes

Keywords

  • adverse effects
  • cutaneous
  • cytotoxic

ASJC Scopus subject areas

  • Dermatology

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