Depression in traumatic brain injury

Victims of traumatic brain injury (TBI) can suffer from profound cognitive and emotional changes. Many patients complain of feeling depressed after a traumatic brain injury, and neuroanatomical and neurochemical changes that occur after TBI may predispose patients to the development of this depression. The differential diagnosis and the prevalence of depressed mood after TBI is discussed. Also discussed are specific therapeutic interventions, including the appropriate use of medication, which can be of significant benefit in helping these patients effectively participate in rehabilitation efforts.