Demonstration of x-ray microscopy with an x-ray laser operating near the carbon K edge

L. B. Da Silva, J. E. Trebes, S. Mrowka, T. W. Barbee, J. Brase, J. A. Koch, R. A. London, B. J. MacGowan, Dennis L Matthews, D. Minyard, G. Stone, T. Yorkey, E. Anderson, D. T. Attwood, D. Kern

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

High-brightness and short-pulse-width (-200 ps) x-ray lasers offer biologists the possibility of high-resolution three-dimensional imaging of specimens in an aqueous environment without the blurring effects associated with natural motions. As a first step toward developing the capabilities of this type of x-ray microscopy we have used a tantalum x-ray laser (λ = 4.483 nm) together with an x-ray zone plate lens to image a test pattern. The observed image shows a detector-limited resolution of approximately 75 nm and paves the way to three-dimensional biological imaging with high spatial resolution (20–30 nm).

Original languageEnglish (US)
Pages (from-to)754-756
Number of pages3
JournalOptics Letters
Volume17
Issue number10
DOIs
StatePublished - May 15 1992
Externally publishedYes

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ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Da Silva, L. B., Trebes, J. E., Mrowka, S., Barbee, T. W., Brase, J., Koch, J. A., London, R. A., MacGowan, B. J., Matthews, D. L., Minyard, D., Stone, G., Yorkey, T., Anderson, E., Attwood, D. T., & Kern, D. (1992). Demonstration of x-ray microscopy with an x-ray laser operating near the carbon K edge. Optics Letters, 17(10), 754-756. https://doi.org/10.1364/OL.17.000754