Demonstration of x-ray microscopy with an x-ray laser operating near the carbon K edge

L. B. Da Silva, J. E. Trebes, S. Mrowka, T. W. Barbee, J. Brase, J. A. Koch, R. A. London, B. J. MacGowan, Dennis L Matthews, D. Minyard, G. Stone, T. Yorkey, E. Anderson, D. T. Attwood, D. Kern

Research output: Contribution to journalArticlepeer-review

45 Scopus citations


High-brightness and short-pulse-width (-200 ps) x-ray lasers offer biologists the possibility of high-resolution three-dimensional imaging of specimens in an aqueous environment without the blurring effects associated with natural motions. As a first step toward developing the capabilities of this type of x-ray microscopy we have used a tantalum x-ray laser (λ = 4.483 nm) together with an x-ray zone plate lens to image a test pattern. The observed image shows a detector-limited resolution of approximately 75 nm and paves the way to three-dimensional biological imaging with high spatial resolution (20–30 nm).

Original languageEnglish (US)
Pages (from-to)754-756
Number of pages3
JournalOptics Letters
Issue number10
StatePublished - May 15 1992
Externally publishedYes

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics


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