Abstract
The authors present a case of a patient with dementia with mood symptoms and multiple neurological manifestations of fragile X-associated tremor/ataxia syndrome (FXTAS). Despite a gradually deteriorating neurological course, he was managed for 2 years with combination therapy of donepezil and venlafaxine, which resulted in improvement and relative stabilization of his psychiatric status. Psychiatrists are hereby alerted to the description of a novel dementia syndrome that may respond to pharmacological intervention commonly used for other dementias.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 171-177 |
| Number of pages | 7 |
| Journal | Journal of Neuropsychiatry and Clinical Neurosciences |
| Volume | 18 |
| Issue number | 2 |
| DOIs | |
| State | Published - Mar 2006 |
ASJC Scopus subject areas
- Neuropsychology and Physiological Psychology
- Neuroscience(all)
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Bourgeois, J. A., Farzin, F., Brunberg, J. A., Tassone, F., Hagerman, P., Zhang, L., Hessl, D., & Hagerman, R. (2006). Dementia with mood symptoms in a fragile X premutation carrier with the fragile X-associated tremor/ataxia syndrome: Clinical intervention with donepezil and venlafaxine. Journal of Neuropsychiatry and Clinical Neurosciences, 18(2), 171-177. https://doi.org/10.1176/appi.neuropsych.18.2.171