delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS.

R. Michael Roe; Peter Y K Cheung; Bruce D. Hammock; Dan Buster; A. Randall Alford

delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS.

R. Michael Roe, Peter Y K Cheung, Bruce D. Hammock, Dan Buster, A. Randall Alford

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The alkaline-dissolved Bacillus thuringiensis israelensis (BTI) delta -endotoxin when introduced by injection was biologically active against a wide spectrum of host animals including insects from four orders and mice. Neuromuscular effects like heart cessation, lost coordination, tremor, and paralysis were observed in test animals. Using the appearance of lactate dehydrogenase in insect hemolymph post-injection as a cytosolic marker, it was found that dissolved BTI delta -endotoxin was cytotoxic.

Original language	English (US)
Title of host publication	ACS Symposium Series
Place of Publication	Washington, DC, USA
Publisher	ACS
Pages	279-292
Number of pages	14
ISBN (Print)	0841209103
State	Published - 1985
Externally published	Yes

ASJC Scopus subject areas

Chemistry(all)

Cite this

delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS. / Roe, R. Michael; Cheung, Peter Y K; Hammock, Bruce D.; Buster, Dan; Alford, A. Randall.

ACS Symposium Series. Washington, DC, USA : ACS, 1985. p. 279-292.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

@inproceedings{40155f9c8c524ef8aab7f44c419de81f,

title = "delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS.",

abstract = "The alkaline-dissolved Bacillus thuringiensis israelensis (BTI) delta -endotoxin when introduced by injection was biologically active against a wide spectrum of host animals including insects from four orders and mice. Neuromuscular effects like heart cessation, lost coordination, tremor, and paralysis were observed in test animals. Using the appearance of lactate dehydrogenase in insect hemolymph post-injection as a cytosolic marker, it was found that dissolved BTI delta -endotoxin was cytotoxic.",

author = "Roe, {R. Michael} and Cheung, {Peter Y K} and Hammock, {Bruce D.} and Dan Buster and Alford, {A. Randall}",

year = "1985",

language = "English (US)",

isbn = "0841209103",

pages = "279--292",

booktitle = "ACS Symposium Series",

publisher = "ACS",

}

TY - GEN

T1 - delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS.

AU - Roe, R. Michael

AU - Cheung, Peter Y K

AU - Hammock, Bruce D.

AU - Buster, Dan

AU - Alford, A. Randall

PY - 1985

Y1 - 1985

N2 - The alkaline-dissolved Bacillus thuringiensis israelensis (BTI) delta -endotoxin when introduced by injection was biologically active against a wide spectrum of host animals including insects from four orders and mice. Neuromuscular effects like heart cessation, lost coordination, tremor, and paralysis were observed in test animals. Using the appearance of lactate dehydrogenase in insect hemolymph post-injection as a cytosolic marker, it was found that dissolved BTI delta -endotoxin was cytotoxic.

AB - The alkaline-dissolved Bacillus thuringiensis israelensis (BTI) delta -endotoxin when introduced by injection was biologically active against a wide spectrum of host animals including insects from four orders and mice. Neuromuscular effects like heart cessation, lost coordination, tremor, and paralysis were observed in test animals. Using the appearance of lactate dehydrogenase in insect hemolymph post-injection as a cytosolic marker, it was found that dissolved BTI delta -endotoxin was cytotoxic.

UR - http://www.scopus.com/inward/record.url?scp=0021787090&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021787090&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:0021787090

SN - 0841209103

SP - 279

EP - 292

BT - ACS Symposium Series

PB - ACS

CY - Washington, DC, USA

ER -

delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS.

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this