The alkaline-dissolved Bacillus thuringiensis israelensis (BTI) delta -endotoxin when introduced by injection was biologically active against a wide spectrum of host animals including insects from four orders and mice. Neuromuscular effects like heart cessation, lost coordination, tremor, and paralysis were observed in test animals. Using the appearance of lactate dehydrogenase in insect hemolymph post-injection as a cytosolic marker, it was found that dissolved BTI delta -endotoxin was cytotoxic.
|Original language||English (US)|
|Title of host publication||ACS Symposium Series|
|Place of Publication||Washington, DC, USA|
|Number of pages||14|
|State||Published - 1985|
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