delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS.

R. Michael Roe; Peter Y K Cheung; Bruce D. Hammock; Dan Buster; A. Randall Alford

delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS.

R. Michael Roe, Peter Y K Cheung, Bruce D. Hammock, Dan Buster, A. Randall Alford

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The alkaline-dissolved Bacillus thuringiensis israelensis (BTI) delta -endotoxin when introduced by injection was biologically active against a wide spectrum of host animals including insects from four orders and mice. Neuromuscular effects like heart cessation, lost coordination, tremor, and paralysis were observed in test animals. Using the appearance of lactate dehydrogenase in insect hemolymph post-injection as a cytosolic marker, it was found that dissolved BTI delta -endotoxin was cytotoxic.

Original language	English (US)
Title of host publication	ACS Symposium Series
Place of Publication	Washington, DC, USA
Publisher	ACS
Pages	279-292
Number of pages	14
ISBN (Print)	0841209103
State	Published - 1985
Externally published	Yes

ASJC Scopus subject areas

Chemistry(all)

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delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS. / Roe, R. Michael; Cheung, Peter Y K; Hammock, Bruce D.; Buster, Dan; Alford, A. Randall.

ACS Symposium Series. Washington, DC, USA : ACS, 1985. p. 279-292.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AU - Cheung, Peter Y K

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AU - Buster, Dan

AU - Alford, A. Randall

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AB - The alkaline-dissolved Bacillus thuringiensis israelensis (BTI) delta -endotoxin when introduced by injection was biologically active against a wide spectrum of host animals including insects from four orders and mice. Neuromuscular effects like heart cessation, lost coordination, tremor, and paralysis were observed in test animals. Using the appearance of lactate dehydrogenase in insect hemolymph post-injection as a cytosolic marker, it was found that dissolved BTI delta -endotoxin was cytotoxic.

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BT - ACS Symposium Series

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ER -

delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS.

Abstract

ASJC Scopus subject areas

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