Abstract
The alkaline-dissolved Bacillus thuringiensis israelensis (BTI) delta -endotoxin when introduced by injection was biologically active against a wide spectrum of host animals including insects from four orders and mice. Neuromuscular effects like heart cessation, lost coordination, tremor, and paralysis were observed in test animals. Using the appearance of lactate dehydrogenase in insect hemolymph post-injection as a cytosolic marker, it was found that dissolved BTI delta -endotoxin was cytotoxic.
| Original language | English (US) |
|---|---|
| Title of host publication | ACS Symposium Series |
| Place of Publication | Washington, DC, USA |
| Publisher | ACS |
| Pages | 279-292 |
| Number of pages | 14 |
| ISBN (Print) | 0841209103 |
| State | Published - 1985 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Chemistry(all)
Cite this
delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS. / Roe, R. Michael; Cheung, Peter Y K; Hammock, Bruce D.; Buster, Dan; Alford, A. Randall.
ACS Symposium Series. Washington, DC, USA : ACS, 1985. p. 279-292.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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TY - GEN
T1 - delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS.
AU - Roe, R. Michael
AU - Cheung, Peter Y K
AU - Hammock, Bruce D.
AU - Buster, Dan
AU - Alford, A. Randall
PY - 1985
Y1 - 1985
N2 - The alkaline-dissolved Bacillus thuringiensis israelensis (BTI) delta -endotoxin when introduced by injection was biologically active against a wide spectrum of host animals including insects from four orders and mice. Neuromuscular effects like heart cessation, lost coordination, tremor, and paralysis were observed in test animals. Using the appearance of lactate dehydrogenase in insect hemolymph post-injection as a cytosolic marker, it was found that dissolved BTI delta -endotoxin was cytotoxic.
AB - The alkaline-dissolved Bacillus thuringiensis israelensis (BTI) delta -endotoxin when introduced by injection was biologically active against a wide spectrum of host animals including insects from four orders and mice. Neuromuscular effects like heart cessation, lost coordination, tremor, and paralysis were observed in test animals. Using the appearance of lactate dehydrogenase in insect hemolymph post-injection as a cytosolic marker, it was found that dissolved BTI delta -endotoxin was cytotoxic.
UR - http://www.scopus.com/inward/record.url?scp=0021787090&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021787090&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0021787090
SN - 0841209103
SP - 279
EP - 292
BT - ACS Symposium Series
PB - ACS
CY - Washington, DC, USA
ER -