delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS.

R. Michael Roe, Peter Y K Cheung, Bruce D. Hammock, Dan Buster, A. Randall Alford

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

The alkaline-dissolved Bacillus thuringiensis israelensis (BTI) delta -endotoxin when introduced by injection was biologically active against a wide spectrum of host animals including insects from four orders and mice. Neuromuscular effects like heart cessation, lost coordination, tremor, and paralysis were observed in test animals. Using the appearance of lactate dehydrogenase in insect hemolymph post-injection as a cytosolic marker, it was found that dissolved BTI delta -endotoxin was cytotoxic.

Original languageEnglish (US)
Title of host publicationACS Symposium Series
Place of PublicationWashington, DC, USA
PublisherACS
Pages279-292
Number of pages14
ISBN (Print)0841209103
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)

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    Roe, R. M., Cheung, P. Y. K., Hammock, B. D., Buster, D., & Alford, A. R. (1985). delta -ENDOTOXIN OF BACILLUS THURINGIENSIS VAR. ISRAELENSIS - BROAD-SPECTRUM TOXICITY AND NEURAL RESPONSE ELICITED IN MICE AND INSECTS. In ACS Symposium Series (pp. 279-292). ACS.