Deep-sea hydrothermal vent bacteria related to human pathogenic Vibrio species

Nur A. Hasan, Christopher J. Grim, Erin K. Lipp, Irma N G Rivera, Jongsik Chun, Bradd J. Haley, Elisa Taviani, Seon Young Choi, Mozammel Hoq, A. Christine Munk, Thomas S. Brettin, David Bruce, Jean F. Challacombe, J. Chris Detter, Cliff S. Han, Jonathan A Eisen, Anwar Huq, Rita R. Colwell

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Vibrio species are both ubiquitous and abundant in marine coastal waters, estuaries, ocean sediment, and aquaculture settings world-wide. We report here the isolation, characterization, and genome sequence of a novel Vibrio species, Vibrio antiquarius, isolated from a mesophilic bacterial community associated with hydrothermal vents located along the East Pacific Rise, near the southwest coast of Mexico. Genomic and phenotypic analysis revealed V. antiquarius is closely related to pathogenic Vibrio species, namely Vibrio alginolyticus, Vibrio parahaemolyticus, Vibrio harveyi, and Vibrio vulnificus, but sufficiently divergent to warrant a separate species status. The V. antiquarius genome encodes genes and operons with ecological functions relevant to the environment conditions of the deep sea and also harbors factors known to be involved in human disease caused by freshwater, coastal, and brackish water vibrios. The presence of virulence factors in this deep-sea Vibrio species suggests a far more fundamental role of these factors for their bacterial host. Comparative genomics revealed a variety of genomic events that may have provided an important driving force in V. antiquarius evolution, facilitating response to environmental conditions of the deep sea.

Original languageEnglish (US)
Pages (from-to)E2813-E2819
JournalProceedings of the National Academy of Sciences of the United States of America
Volume112
Issue number21
DOIs
StatePublished - May 26 2015

Fingerprint

Hydrothermal Vents
Vibrio
Bacteria
Oceans and Seas
Vibrio alginolyticus
Genome
Vibrio vulnificus
Vibrio parahaemolyticus
Estuaries
Aquaculture
Virulence Factors
Operon
Genomics
Mexico
Fresh Water
Water

Keywords

  • EX25
  • Genomics
  • Hydrothermal vent
  • Vibrio

ASJC Scopus subject areas

  • General

Cite this

Hasan, N. A., Grim, C. J., Lipp, E. K., Rivera, I. N. G., Chun, J., Haley, B. J., ... Colwell, R. R. (2015). Deep-sea hydrothermal vent bacteria related to human pathogenic Vibrio species. Proceedings of the National Academy of Sciences of the United States of America, 112(21), E2813-E2819. https://doi.org/10.1073/pnas.1503928112

Deep-sea hydrothermal vent bacteria related to human pathogenic Vibrio species. / Hasan, Nur A.; Grim, Christopher J.; Lipp, Erin K.; Rivera, Irma N G; Chun, Jongsik; Haley, Bradd J.; Taviani, Elisa; Choi, Seon Young; Hoq, Mozammel; Munk, A. Christine; Brettin, Thomas S.; Bruce, David; Challacombe, Jean F.; Detter, J. Chris; Han, Cliff S.; Eisen, Jonathan A; Huq, Anwar; Colwell, Rita R.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, No. 21, 26.05.2015, p. E2813-E2819.

Research output: Contribution to journalArticle

Hasan, NA, Grim, CJ, Lipp, EK, Rivera, ING, Chun, J, Haley, BJ, Taviani, E, Choi, SY, Hoq, M, Munk, AC, Brettin, TS, Bruce, D, Challacombe, JF, Detter, JC, Han, CS, Eisen, JA, Huq, A & Colwell, RR 2015, 'Deep-sea hydrothermal vent bacteria related to human pathogenic Vibrio species', Proceedings of the National Academy of Sciences of the United States of America, vol. 112, no. 21, pp. E2813-E2819. https://doi.org/10.1073/pnas.1503928112
Hasan, Nur A. ; Grim, Christopher J. ; Lipp, Erin K. ; Rivera, Irma N G ; Chun, Jongsik ; Haley, Bradd J. ; Taviani, Elisa ; Choi, Seon Young ; Hoq, Mozammel ; Munk, A. Christine ; Brettin, Thomas S. ; Bruce, David ; Challacombe, Jean F. ; Detter, J. Chris ; Han, Cliff S. ; Eisen, Jonathan A ; Huq, Anwar ; Colwell, Rita R. / Deep-sea hydrothermal vent bacteria related to human pathogenic Vibrio species. In: Proceedings of the National Academy of Sciences of the United States of America. 2015 ; Vol. 112, No. 21. pp. E2813-E2819.
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