Decay of colostral antibodies to bovine leukemia virus with application to detection of calfhood infection.

Mark Thurmond, R. L. Carter, D. M. Puhr, M. J. Burridge

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

An estimated weighted-regression method was used to describe the decay of colostral bovine leukemia virus (BLV) antibodies in the calf, as measured by agar-gel immunodiffusion with glycoprotein antigen. The prediction equation, based on 473 observations from 130 animals, was log10 inverse titer = 1.29 -0.012 age (days). The half-life of BLV antibodies was estimated to be 25.8 days. Ages at which colostral antibodies were last detected were between 51 and 187 days. Normal limits of antibody decay were estimated and used to identify virus-induced active antibodies in calves during the colostral antibody period. Calves known to be infected were identified between 2 and 180 days of age, using 95% limits. Application of this procedure for the early serologic detection of BLV-infected calves in eradication or control programs is discussed.

Original languageEnglish (US)
Pages (from-to)1152-1155
Number of pages4
JournalAmerican Journal of Veterinary Research
Volume43
Issue number7
StatePublished - Jul 1 1982
Externally publishedYes

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Bovine Leukemia Virus
Bovine leukemia virus
deterioration
antibodies
Antibodies
Infection
calves
infection
Immunodiffusion
half life
Agar
Half-Life
glycoproteins
Glycoproteins
agar
Gels
gels
Viruses
antigens
Antigens

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Decay of colostral antibodies to bovine leukemia virus with application to detection of calfhood infection. / Thurmond, Mark; Carter, R. L.; Puhr, D. M.; Burridge, M. J.

In: American Journal of Veterinary Research, Vol. 43, No. 7, 01.07.1982, p. 1152-1155.

Research output: Contribution to journalArticle

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