Abstract
An estimated weighted-regression method was used to describe the decay of colostral bovine leukemia virus (BLV) antibodies in the calf, as measured by agar-gel immunodiffusion with glycoprotein antigen. The prediction equation, based on 473 observations from 130 animals, was log10 inverse titer = 1.29 -0.012 age (days). The half-life of BLV antibodies was estimated to be 25.8 days. Ages at which colostral antibodies were last detected were between 51 and 187 days. Normal limits of antibody decay were estimated and used to identify virus-induced active antibodies in calves during the colostral antibody period. Calves known to be infected were identified between 2 and 180 days of age, using 95% limits. Application of this procedure for the early serologic detection of BLV-infected calves in eradication or control programs is discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1152-1155 |
| Number of pages | 4 |
| Journal | American Journal of Veterinary Research |
| Volume | 43 |
| Issue number | 7 |
| State | Published - Jul 1 1982 |
| Externally published | Yes |
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- veterinary(all)
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Decay of colostral antibodies to bovine leukemia virus with application to detection of calfhood infection. / Thurmond, Mark; Carter, R. L.; Puhr, D. M.; Burridge, M. J.
In: American Journal of Veterinary Research, Vol. 43, No. 7, 01.07.1982, p. 1152-1155.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Decay of colostral antibodies to bovine leukemia virus with application to detection of calfhood infection.
AU - Thurmond, Mark
AU - Carter, R. L.
AU - Puhr, D. M.
AU - Burridge, M. J.
PY - 1982/7/1
Y1 - 1982/7/1
N2 - An estimated weighted-regression method was used to describe the decay of colostral bovine leukemia virus (BLV) antibodies in the calf, as measured by agar-gel immunodiffusion with glycoprotein antigen. The prediction equation, based on 473 observations from 130 animals, was log10 inverse titer = 1.29 -0.012 age (days). The half-life of BLV antibodies was estimated to be 25.8 days. Ages at which colostral antibodies were last detected were between 51 and 187 days. Normal limits of antibody decay were estimated and used to identify virus-induced active antibodies in calves during the colostral antibody period. Calves known to be infected were identified between 2 and 180 days of age, using 95% limits. Application of this procedure for the early serologic detection of BLV-infected calves in eradication or control programs is discussed.
AB - An estimated weighted-regression method was used to describe the decay of colostral bovine leukemia virus (BLV) antibodies in the calf, as measured by agar-gel immunodiffusion with glycoprotein antigen. The prediction equation, based on 473 observations from 130 animals, was log10 inverse titer = 1.29 -0.012 age (days). The half-life of BLV antibodies was estimated to be 25.8 days. Ages at which colostral antibodies were last detected were between 51 and 187 days. Normal limits of antibody decay were estimated and used to identify virus-induced active antibodies in calves during the colostral antibody period. Calves known to be infected were identified between 2 and 180 days of age, using 95% limits. Application of this procedure for the early serologic detection of BLV-infected calves in eradication or control programs is discussed.
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M3 - Article
VL - 43
SP - 1152
EP - 1155
JO - American Journal of Veterinary Research
JF - American Journal of Veterinary Research
SN - 0002-9645
IS - 7
ER -