Deal breaker: semaphorin and specificity in the spinal stretch reflex circuit.

Géraldine S. Maro, Kang Shen, Hwai-Jong Cheng

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Stretch reflex circuits are a prime example of wiring specificity in the vertebrate spinal cord. Homonymous sensory afferents and motoneurons typically form monosynaptic connections, while neurons innervating antagonistic or unrelated muscles do not. Pecho-Vrieseling et al. now show that the semaphorin Sema3E and its receptor Plexin-D1 prevent monosynaptic connectivity in the cutaneous maximus muscle stretch reflex circuit.

Original languageEnglish (US)
Pages (from-to)8-11
Number of pages4
JournalNeuron
Volume63
Issue number1
StatePublished - Jul 16 2009
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

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  • Cite this

    Maro, G. S., Shen, K., & Cheng, H-J. (2009). Deal breaker: semaphorin and specificity in the spinal stretch reflex circuit. Neuron, 63(1), 8-11.