Abstract
Stretch reflex circuits are a prime example of wiring specificity in the vertebrate spinal cord. Homonymous sensory afferents and motoneurons typically form monosynaptic connections, while neurons innervating antagonistic or unrelated muscles do not. Pecho-Vrieseling et al. now show that the semaphorin Sema3E and its receptor Plexin-D1 prevent monosynaptic connectivity in the cutaneous maximus muscle stretch reflex circuit.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 8-11 |
| Number of pages | 4 |
| Journal | Neuron |
| Volume | 63 |
| Issue number | 1 |
| State | Published - Jul 16 2009 |
| Externally published | Yes |
ASJC Scopus subject areas
- Neuroscience(all)
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Cite this
Maro, G. S., Shen, K., & Cheng, H-J. (2009). Deal breaker: semaphorin and specificity in the spinal stretch reflex circuit. Neuron, 63(1), 8-11.