Deal breaker: semaphorin and specificity in the spinal stretch reflex circuit.

Géraldine S. Maro; Kang Shen; Hwai-Jong Cheng

Deal breaker: semaphorin and specificity in the spinal stretch reflex circuit.

Géraldine S. Maro, Kang Shen, Hwai-Jong Cheng

Research output: Contribution to journal › Article › peer-review

Abstract

Stretch reflex circuits are a prime example of wiring specificity in the vertebrate spinal cord. Homonymous sensory afferents and motoneurons typically form monosynaptic connections, while neurons innervating antagonistic or unrelated muscles do not. Pecho-Vrieseling et al. now show that the semaphorin Sema3E and its receptor Plexin-D1 prevent monosynaptic connectivity in the cutaneous maximus muscle stretch reflex circuit.

Original language	English (US)
Pages (from-to)	8-11
Number of pages	4
Journal	Neuron
Volume	63
Issue number	1
State	Published - Jul 16 2009
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)

Cite this

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Deal breaker: semaphorin and specificity in the spinal stretch reflex circuit.

Abstract

ASJC Scopus subject areas

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