Daylight-induced antibacterial and antiviral nanofibrous membranes containing Vitamin K derivatives for personal protective equipment

Gang Sun, Zheng Zhang, Ahmed Y. El-Moghazy, Nicharee Wisuthiphaet, Nitin Nitin, Diego Castillo, Brian G. Murphy

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

During the development of antibacterial and antiviral materials for personal protective equipment (PPE), daylight active functional polymeric materials containing vitamin K compounds (VKs) and impacts of polymer structures to the functions were investigated. As examples, hydrophobic polyacrylonitrile (PAN) and hydrophilic poly(vinyl alcohol-co-ethylene) (PVA-co-PE) polymers were directly blended with three VK compounds and electrospun into VK-containing nanofibrous membranes (VNFMs). The prepared VNFMs exhibited robust photoactivity in generating reactive oxygen species (ROS) under both daylight (D65, 300−800 nm) and ultraviolet A (UVA, 365 nm) irradiation, resulting in high antimicrobial and antiviral efficiency (>99.9%) within a short exposure time (<90 min). Interestingly, the PVA-co-PE/VK3 VNFM showed higher ROS production rates and better biocidal functions than those of the PAN/VK3 VNFM under the same photoirradiation conditions, indicating that PVA-coPE is a better matrix polymer material for these functions. Moreover, the prepared PVA-co-PE/VK3 VNFM maintains its powerful microbicidal function even after five times of repeated exposures to bacteria and viruses, showing the stability and reusability of the antimicrobial materials. The fabrication of photoinduced antimicrobial VNFMs may provide new insights into the development of non-toxic and reusable photoinduced antimicrobial materials that could be applied in personal protective equipment with improved biological protections.

Original languageEnglish (US)
JournalACS Applied Materials and Interfaces
DOIs
StateAccepted/In press - 2020

Keywords

  • Biocidal PPE
  • Nanofibrous membranes
  • Photoinduced antimicrobial and antiviral
  • Photoinduced generation of reactive oxygen species
  • Vitamin K derivatives

ASJC Scopus subject areas

  • Materials Science(all)

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