Damage to tissue defenses by vasoconstrictors

Thomas R Stevenson; George T. Rodeheaver; Gerald T. Golden; Milton T. Edgerton; James H. Wells; Richard F. Edlich

doi:10.1016/S0361-1124(75)80035-9

Damage to tissue defenses by vasoconstrictors

Thomas R Stevenson, George T. Rodeheaver, Gerald T. Golden, Milton T. Edgerton, James H. Wells, Richard F. Edlich

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

The paper investigates the effect of solutions of local anesthetic agents on the ability of wounds to resist infection as well as the influence of the injection techniques on the dissemination of bacteria through the wound. On the basis of these studies, the following recommendations are made: (1) a regional nerve block with 1% lidocaine administered through a 27 gauge needle is indicated before wound cleansing; (2) if the wound is not susceptible to a regional nerve block, anesthetize the wound by injecting the agent through the skin around the periphery of the wound; (3) avoid the use of epinephrine with the anesthetic agent.

Original language	English (US)
Pages (from-to)	532-535
Number of pages	4
Journal	Journal of the American College of Emergency Physicians
Volume	4
Issue number	6
DOIs	https://doi.org/10.1016/S0361-1124(75)80035-9
State	Published - 1975
Externally published	Yes

Keywords

anesthesia
epinephrine
lidocaine
vasoconstrictors
wound infection

ASJC Scopus subject areas

Critical Care and Intensive Care Medicine

Access to Document

10.1016/S0361-1124(75)80035-9

Cite this

@article{312e232558a743998c41af02e9c7adc6,

title = "Damage to tissue defenses by vasoconstrictors",

abstract = "The paper investigates the effect of solutions of local anesthetic agents on the ability of wounds to resist infection as well as the influence of the injection techniques on the dissemination of bacteria through the wound. On the basis of these studies, the following recommendations are made: (1) a regional nerve block with 1% lidocaine administered through a 27 gauge needle is indicated before wound cleansing; (2) if the wound is not susceptible to a regional nerve block, anesthetize the wound by injecting the agent through the skin around the periphery of the wound; (3) avoid the use of epinephrine with the anesthetic agent.",

keywords = "anesthesia, epinephrine, lidocaine, vasoconstrictors, wound infection",

author = "Stevenson, {Thomas R} and Rodeheaver, {George T.} and Golden, {Gerald T.} and Edgerton, {Milton T.} and Wells, {James H.} and Edlich, {Richard F.}",

year = "1975",

doi = "10.1016/S0361-1124(75)80035-9",

language = "English (US)",

volume = "4",

pages = "532--535",

journal = "Journal of the American College of Emergency Physicians",

issn = "0196-0644",

publisher = "Mosby Inc.",

number = "6",

}

TY - JOUR

T1 - Damage to tissue defenses by vasoconstrictors

AU - Stevenson, Thomas R

AU - Rodeheaver, George T.

AU - Golden, Gerald T.

AU - Edgerton, Milton T.

AU - Wells, James H.

AU - Edlich, Richard F.

PY - 1975

Y1 - 1975

N2 - The paper investigates the effect of solutions of local anesthetic agents on the ability of wounds to resist infection as well as the influence of the injection techniques on the dissemination of bacteria through the wound. On the basis of these studies, the following recommendations are made: (1) a regional nerve block with 1% lidocaine administered through a 27 gauge needle is indicated before wound cleansing; (2) if the wound is not susceptible to a regional nerve block, anesthetize the wound by injecting the agent through the skin around the periphery of the wound; (3) avoid the use of epinephrine with the anesthetic agent.

AB - The paper investigates the effect of solutions of local anesthetic agents on the ability of wounds to resist infection as well as the influence of the injection techniques on the dissemination of bacteria through the wound. On the basis of these studies, the following recommendations are made: (1) a regional nerve block with 1% lidocaine administered through a 27 gauge needle is indicated before wound cleansing; (2) if the wound is not susceptible to a regional nerve block, anesthetize the wound by injecting the agent through the skin around the periphery of the wound; (3) avoid the use of epinephrine with the anesthetic agent.

KW - anesthesia

KW - epinephrine

KW - lidocaine

KW - vasoconstrictors

KW - wound infection

UR - http://www.scopus.com/inward/record.url?scp=0016716093&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016716093&partnerID=8YFLogxK

U2 - 10.1016/S0361-1124(75)80035-9

DO - 10.1016/S0361-1124(75)80035-9

M3 - Article

AN - SCOPUS:0016716093

VL - 4

SP - 532

EP - 535

JO - Journal of the American College of Emergency Physicians

JF - Journal of the American College of Emergency Physicians

SN - 0196-0644

IS - 6

ER -

Damage to tissue defenses by vasoconstrictors

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this