Damage to tissue defenses by vasoconstrictors

Thomas R Stevenson; George T. Rodeheaver; Gerald T. Golden; Milton T. Edgerton; James H. Wells; Richard F. Edlich

doi:10.1016/S0361-1124(75)80035-9

Damage to tissue defenses by vasoconstrictors

Thomas R Stevenson, George T. Rodeheaver, Gerald T. Golden, Milton T. Edgerton, James H. Wells, Richard F. Edlich

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The paper investigates the effect of solutions of local anesthetic agents on the ability of wounds to resist infection as well as the influence of the injection techniques on the dissemination of bacteria through the wound. On the basis of these studies, the following recommendations are made: (1) a regional nerve block with 1% lidocaine administered through a 27 gauge needle is indicated before wound cleansing; (2) if the wound is not susceptible to a regional nerve block, anesthetize the wound by injecting the agent through the skin around the periphery of the wound; (3) avoid the use of epinephrine with the anesthetic agent.

Original language	English (US)
Pages (from-to)	532-535
Number of pages	4
Journal	Journal of the American College of Emergency Physicians
Volume	4
Issue number	6
DOIs	https://doi.org/10.1016/S0361-1124(75)80035-9
State	Published - 1975
Externally published	Yes

Keywords

anesthesia
epinephrine
lidocaine
vasoconstrictors
wound infection

ASJC Scopus subject areas

Critical Care and Intensive Care Medicine

Access to Document

10.1016/S0361-1124(75)80035-9

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abstract = "The paper investigates the effect of solutions of local anesthetic agents on the ability of wounds to resist infection as well as the influence of the injection techniques on the dissemination of bacteria through the wound. On the basis of these studies, the following recommendations are made: (1) a regional nerve block with 1% lidocaine administered through a 27 gauge needle is indicated before wound cleansing; (2) if the wound is not susceptible to a regional nerve block, anesthetize the wound by injecting the agent through the skin around the periphery of the wound; (3) avoid the use of epinephrine with the anesthetic agent.",

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AU - Stevenson, Thomas R

AU - Rodeheaver, George T.

AU - Golden, Gerald T.

AU - Edgerton, Milton T.

AU - Wells, James H.

AU - Edlich, Richard F.

PY - 1975

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AB - The paper investigates the effect of solutions of local anesthetic agents on the ability of wounds to resist infection as well as the influence of the injection techniques on the dissemination of bacteria through the wound. On the basis of these studies, the following recommendations are made: (1) a regional nerve block with 1% lidocaine administered through a 27 gauge needle is indicated before wound cleansing; (2) if the wound is not susceptible to a regional nerve block, anesthetize the wound by injecting the agent through the skin around the periphery of the wound; (3) avoid the use of epinephrine with the anesthetic agent.

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KW - epinephrine

KW - lidocaine

KW - vasoconstrictors

KW - wound infection

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