Abstract
Dairy food enhances weight loss in animal models, possibly by modifying the metabolic effects of cortisol. This study determined in overweight women (ages 20.0-45.9 y; n = 51) whether including dairy food in an energy-restricted diet affects cortisol concentrations and whether differences in provoked cortisol explain the magnitude of weight loss. Women received either an adequate amount of dairy food (AD), the equivalent of ≤711 mL/d milk, or a low amount of dairy food (LD), theequivalent to ≥238 mL/d milk, in a 12-wk, energy-restricted dietary intervention. Participants were tested in a 12-hlaboratory visit, which included 2 standard meals and a dinner buffet that was consumed ad libitum. Salivary cortisol was measured from waking to bedtime. Energy restriction increased (P ≥ 0.04) the minimum and decreased (P ≥ 0.02) the diurnal amplitude in the salivary cortisol concentration from baseline to postintervention. Energy restriction enhanced the dinner meal- stimulated salivary cortisol response (DMR) (P ≥ 0.02) but only in the LD group. Compared with the LD treatment, the AD treatment induced (P ≥ 0.04) greater reductions in body weight and fat, but only in women characterized as having a baselineDMR(responders) (n = 26);weight and fat lost in the AD and LD groups were similar in nonresponders (n =25).Overall, energy restriction dampened diurnal salivary cortisol fluctuations [symptomatic of hypothalamic-pituitary-adrenal (HPA) axis dysfunction] and enhanced dinner meal-stimulated salivary cortisol concentrations. The AD treatment prevented the latter. Furthermore, certain phenotypic markers of HPA axis function may help to expose the weight-reducing effects of consuming dairy food.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 46-52 |
| Number of pages | 7 |
| Journal | Journal of Nutrition |
| Volume | 143 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2013 |
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ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics
Cite this
Dairy food consumption and meal-induced cortisol response interacted to influence weight loss in overweight women undergoing a 12-week, meal-controlled, weight loss intervention. / Witbracht, Megan G.; Van Loan, Marta; Adams, Sean H.; Keim, Nancy L.; Laugero, Kevin D.
In: Journal of Nutrition, Vol. 143, No. 1, 01.2013, p. 46-52.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dairy food consumption and meal-induced cortisol response interacted to influence weight loss in overweight women undergoing a 12-week, meal-controlled, weight loss intervention
AU - Witbracht, Megan G.
AU - Van Loan, Marta
AU - Adams, Sean H.
AU - Keim, Nancy L.
AU - Laugero, Kevin D.
PY - 2013/1
Y1 - 2013/1
N2 - Dairy food enhances weight loss in animal models, possibly by modifying the metabolic effects of cortisol. This study determined in overweight women (ages 20.0-45.9 y; n = 51) whether including dairy food in an energy-restricted diet affects cortisol concentrations and whether differences in provoked cortisol explain the magnitude of weight loss. Women received either an adequate amount of dairy food (AD), the equivalent of ≤711 mL/d milk, or a low amount of dairy food (LD), theequivalent to ≥238 mL/d milk, in a 12-wk, energy-restricted dietary intervention. Participants were tested in a 12-hlaboratory visit, which included 2 standard meals and a dinner buffet that was consumed ad libitum. Salivary cortisol was measured from waking to bedtime. Energy restriction increased (P ≥ 0.04) the minimum and decreased (P ≥ 0.02) the diurnal amplitude in the salivary cortisol concentration from baseline to postintervention. Energy restriction enhanced the dinner meal- stimulated salivary cortisol response (DMR) (P ≥ 0.02) but only in the LD group. Compared with the LD treatment, the AD treatment induced (P ≥ 0.04) greater reductions in body weight and fat, but only in women characterized as having a baselineDMR(responders) (n = 26);weight and fat lost in the AD and LD groups were similar in nonresponders (n =25).Overall, energy restriction dampened diurnal salivary cortisol fluctuations [symptomatic of hypothalamic-pituitary-adrenal (HPA) axis dysfunction] and enhanced dinner meal-stimulated salivary cortisol concentrations. The AD treatment prevented the latter. Furthermore, certain phenotypic markers of HPA axis function may help to expose the weight-reducing effects of consuming dairy food.
AB - Dairy food enhances weight loss in animal models, possibly by modifying the metabolic effects of cortisol. This study determined in overweight women (ages 20.0-45.9 y; n = 51) whether including dairy food in an energy-restricted diet affects cortisol concentrations and whether differences in provoked cortisol explain the magnitude of weight loss. Women received either an adequate amount of dairy food (AD), the equivalent of ≤711 mL/d milk, or a low amount of dairy food (LD), theequivalent to ≥238 mL/d milk, in a 12-wk, energy-restricted dietary intervention. Participants were tested in a 12-hlaboratory visit, which included 2 standard meals and a dinner buffet that was consumed ad libitum. Salivary cortisol was measured from waking to bedtime. Energy restriction increased (P ≥ 0.04) the minimum and decreased (P ≥ 0.02) the diurnal amplitude in the salivary cortisol concentration from baseline to postintervention. Energy restriction enhanced the dinner meal- stimulated salivary cortisol response (DMR) (P ≥ 0.02) but only in the LD group. Compared with the LD treatment, the AD treatment induced (P ≥ 0.04) greater reductions in body weight and fat, but only in women characterized as having a baselineDMR(responders) (n = 26);weight and fat lost in the AD and LD groups were similar in nonresponders (n =25).Overall, energy restriction dampened diurnal salivary cortisol fluctuations [symptomatic of hypothalamic-pituitary-adrenal (HPA) axis dysfunction] and enhanced dinner meal-stimulated salivary cortisol concentrations. The AD treatment prevented the latter. Furthermore, certain phenotypic markers of HPA axis function may help to expose the weight-reducing effects of consuming dairy food.
UR - http://www.scopus.com/inward/record.url?scp=84872179369&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84872179369&partnerID=8YFLogxK
U2 - 10.3945/jn.112.166355
DO - 10.3945/jn.112.166355
M3 - Article
C2 - 23190756
AN - SCOPUS:84872179369
VL - 143
SP - 46
EP - 52
JO - Journal of Nutrition
JF - Journal of Nutrition
SN - 0022-3166
IS - 1
ER -