Daily Living Skills in Adolescent and Young Adult Males With Fragile X Syndrome

Angela John Thurman, Stephanie Summers Swinehart, Jessica Klusek, Jane E. Roberts, Lauren Bullard, Jocelyn Christina B. Marzan, W. Ted Brown, Leonard Abbeduto

Research output: Contribution to journalArticlepeer-review


By adulthood, most males with fragile X syndrome (FXS) require support to navigate day-to-day settings. The present study cross-sectionally: (1) characterized the profile of daily living skills in males with FXS and (2) examined associated participant characteristics (i.e., fragile X mental retardation protein [FMRP] expression, nonverbal cognition, language, autism symptomatology, and anxiety symptomatology) using the Waisman-Activities of Daily Living questionnaire. Males with FXS (n = 57, ages 15-23 years) needed more help/support in the areas of domestic and community daily livings skills, than in the area of personal daily living skills. Significant associations were observed between reduced daily living skills and lower nonverbal cognition, receptive language, expressive language, and increased autism symptomatology. Receptive language emerged as the strongest unique predictor of daily living skill performance.

Original languageEnglish (US)
Pages (from-to)64-83
Number of pages20
JournalAmerican journal on intellectual and developmental disabilities
Issue number1
StatePublished - Jan 1 2022
Externally publishedYes


  • autism spectrum disorder
  • daily living skills
  • FMRP
  • fragile X syndrome
  • language

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neuropsychology and Physiological Psychology
  • Developmental and Educational Psychology
  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Psychiatry and Mental health


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