Daily feeding of diclazuril top dress pellets in foals reduces seroconversion to Sarcocystis neurona

Nicola Pusterla, Andrea Packham, Sarah Mackie, Philip H Kass, Laszlo Hunyadi, Patricia A Conrad

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Thirty-three foals from a farm with a high exposure rate to Sarcocystis neurona were assigned to either an untreated or a diclazuril-treated group. Treated foals received daily 0.5 mg/kg of diclazuril pellets from 1 to 12 months of age. Monthly blood was tested for IgG against S. neurona using the indirect fluorescent antibody test. Following ingestion of colostral antibodies to S. neurona, there was a steady and continuous decline in seroprevalence to S. neurona until foals from both groups reached weaning age. Thereafter, the untreated foal group showed a significant increase in monthly seroprevalence compared to the diclazuril-treated foal group. The difference in temporal seroprevalence could be explained by the successful reduction of S. neurona infection in foals receiving a daily low-dose diclazuril.

Original languageEnglish (US)
Pages (from-to)236-238
Number of pages3
JournalVeterinary Journal
Volume206
Issue number2
DOIs
StatePublished - Nov 1 2015

Fingerprint

diclazuril
Sarcocystis
Sarcocystis neurona
seroconversion
foals
pellets
Seroepidemiologic Studies
seroprevalence
Antibodies
Weaning
antibodies
Eating
Immunoglobulin G
Seroconversion
weaning
Infection
ingestion

Keywords

  • Diclazuril
  • Horses
  • Indirect fluorescence antibody test
  • Prevention
  • Sarcocystis neurona

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Daily feeding of diclazuril top dress pellets in foals reduces seroconversion to Sarcocystis neurona. / Pusterla, Nicola; Packham, Andrea; Mackie, Sarah; Kass, Philip H; Hunyadi, Laszlo; Conrad, Patricia A.

In: Veterinary Journal, Vol. 206, No. 2, 01.11.2015, p. 236-238.

Research output: Contribution to journalArticle

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