D-dimer analysis in dogs with hypercoagulable diseases

Ta Liang Ku, Hyung Jin Park, Kyoung Won Seo, Kun Ho Song

Research output: Contribution to journalArticlepeer-review


Total 283 dogs were enrolled in this study (control group: 140, patient group: 143). In the patient group, 143 dogs with underlying diseases including immune medicated hemolytic anemia (IMHA) (7), lymphoma (30), hyperadrenocorticism (HAC) (16), trauma (10), pyometra (8), bone fracture (38), peritonitis (13), meningoencephalitis (12) and mitral regurgitation (9) were enrolled in this study. Compared with healthy group, lymphoma, trauma, HAC, and IMHA group showed significantly (P < 0.01) high values of D-dimer and the highest levels in the IMHA group. Additionally, we evaluated the D-dimer level after a week of enoxaparin treatment, and the results showed D-dimer levels of post treatment group were significantly decreased compared to the pre-treatment group in lymphoma, HAC, trauma and IMHA diseases. In the high level D-dimer group, post D-dimer values after enoxaparin treatment had significantly decreased (P < 0.01) compared to levels prior to treatment.

Original languageEnglish (US)
Pages (from-to)401-403
Number of pages3
JournalJournal of Veterinary Clinics
Issue number6
StatePublished - Dec 1 2017
Externally publishedYes


  • D-dimer
  • Dog
  • Enoxaparin
  • Levels
  • Underlying diseases

ASJC Scopus subject areas

  • veterinary(all)


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