Cytokines in liver health and disease

Pietro Invernizzi; Ilaria Bianchi; Massimo Locati; Raffaella Bonecchi; Carlo Selmi

doi:10.1007/978-1-59745-518-3_8

Cytokines in liver health and disease

Pietro Invernizzi, Ilaria Bianchi, Massimo Locati, Raffaella Bonecchi, Carlo Selmi

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

Cytokines are soluble peptides secreted by several kinds of cells, they mediate many immune and inflammatory reactions, and regulate several biochemical processes in and around the cells that produce them. They may act on different cell types (pleiotropic effects) and have overlapping effects (redundancy); furthermore, their action may be local or systemic. In most tissues, including the liver, constitutive production of cytokines is absent or minimal. However, as physiologic and pathologic stimuli activate cells, the production of these molecules increases, and they orchestrate the tissue's response to the stimulus. Phenotype of the immune response is a function of the repertoire of cytokines produced in the early phases (1).

Original language	English (US)
Title of host publication	Liver Immunology: Principles and Practice
Publisher	Humana Press
Pages	83-93
Number of pages	11
ISBN (Print)	9781588298188
DOIs	https://doi.org/10.1007/978-1-59745-518-3_8
State	Published - 2007
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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abstract = "Cytokines are soluble peptides secreted by several kinds of cells, they mediate many immune and inflammatory reactions, and regulate several biochemical processes in and around the cells that produce them. They may act on different cell types (pleiotropic effects) and have overlapping effects (redundancy); furthermore, their action may be local or systemic. In most tissues, including the liver, constitutive production of cytokines is absent or minimal. However, as physiologic and pathologic stimuli activate cells, the production of these molecules increases, and they orchestrate the tissue's response to the stimulus. Phenotype of the immune response is a function of the repertoire of cytokines produced in the early phases (1).",

author = "Pietro Invernizzi and Ilaria Bianchi and Massimo Locati and Raffaella Bonecchi and Carlo Selmi",

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T1 - Cytokines in liver health and disease

AU - Invernizzi, Pietro

AU - Bianchi, Ilaria

AU - Locati, Massimo

AU - Bonecchi, Raffaella

AU - Selmi, Carlo

PY - 2007

Y1 - 2007

N2 - Cytokines are soluble peptides secreted by several kinds of cells, they mediate many immune and inflammatory reactions, and regulate several biochemical processes in and around the cells that produce them. They may act on different cell types (pleiotropic effects) and have overlapping effects (redundancy); furthermore, their action may be local or systemic. In most tissues, including the liver, constitutive production of cytokines is absent or minimal. However, as physiologic and pathologic stimuli activate cells, the production of these molecules increases, and they orchestrate the tissue's response to the stimulus. Phenotype of the immune response is a function of the repertoire of cytokines produced in the early phases (1).

AB - Cytokines are soluble peptides secreted by several kinds of cells, they mediate many immune and inflammatory reactions, and regulate several biochemical processes in and around the cells that produce them. They may act on different cell types (pleiotropic effects) and have overlapping effects (redundancy); furthermore, their action may be local or systemic. In most tissues, including the liver, constitutive production of cytokines is absent or minimal. However, as physiologic and pathologic stimuli activate cells, the production of these molecules increases, and they orchestrate the tissue's response to the stimulus. Phenotype of the immune response is a function of the repertoire of cytokines produced in the early phases (1).

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BT - Liver Immunology: Principles and Practice

PB - Humana Press

ER -

Cytokines in liver health and disease

Abstract

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